نتایج جستجو برای: thrombocytopenic purpura
تعداد نتایج: 13583 فیلتر نتایج به سال:
Abnormalities of plasma von Willebrand factor (VWF) have been recognized to be associated with thrombotic thrombocytopenic purpura (TTP) for over 20 years. Patients with chronic, relapsing TTP have VWF multimers that are larger than normal, similar in size to those secreted by cultured endothelial cells. Recent observations have documented that a deficiency of a VWF-cleaving protease (termed AD...
Examination of the bone marrow in thrombocytopenic purpura shows two main patterns: the megakaryocytes are either deficient or else present in normal or even increased numbers. The former group results from depression of the marrow as by poisoning or mechanical displacement of the cells themselves by foreign tissue in leukaemia, infiltration with malignant cells, replacement with bone or fibrou...
Anti-ADAMTS13 autoantibodies are the main cause of acquired thrombotic thrombocytopenic purpura. Binding of these antibodies to ADAMTS13 eventually results in the formation of antigen-antibody immune complexes. Circulating ADAMTS13-specific immune complexes have been described in patients with acquired thrombotic thrombocytopenic purpura, although the prevalence and persistence of these immune ...
Etiologies for diffuse alveolar hemorrhage are wide and range from infectious to vasculitis and malignant processes. Idiopathic thrombocytopenic purpura is an autoimmune disorder characterized by persistent thrombocytopenia, with a relatively indolent course in young patients, but a more complicated progression and high associated mortality in the older patients. Diffuse alveolar hemorrhage, co...
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