نتایج جستجو برای: thrombomodulin
تعداد نتایج: 1700 فیلتر نتایج به سال:
The serpins antithrombin (AT) and protein C inhibitor (PCI) inhibit thrombin in a reaction that is accelerated by heparin (1000-fold and 40-fold respectively). The heparin binding domains of PCI and AT differ. In AT, the D-helix is a major part of the heparin-binding domain, while the H-helix is the heparin-binding domain in PCI. Compared to antithrombin, PCI is a more potent inhibitor of throm...
To clarify the relation between systemic and cutaneous vascular endothelial injury in progressive systemic sclerosis (PSS), we examined thrombomodulin (TM) expression in PSS skin lesions immuno-histopathologically and compared it with plasma soluble TM levels measured by specific enzyme-linked immunosorbent assay. The plasma soluble TM level in PSS patients was significantly higher than that of...
Well-aligned nanopatterns of various serum, antithrombogenic and cell adhesive proteins, such as gamma-globulin, fibrinogen, thrombomodulin, fibronectin and type I collagen, were fabricated on a highly-oriented block copolymer lamellar surface, and these bioactive protein nanoarrays will be useful in biological research.
We report a 14-year-old girl, who developed shigatoxin-producing E. coli (STEC)-HUS complicated by encephalopathy. She was successfully treated with hemodiafiltration, high-dose methylprednisolone pulse therapy, and soluble recombinant thrombomodulin under plasma exchange. von Willebrand factor multimers analysis provides potential insights into how the administered therapies might facilitate s...
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