Iodine is an effective, simple, and cost-efficient means of water disinfection for people who vacation, travel, or work in areas where municipal water treatment is not reliable. However, there is considerable controversy about the maximum safe iodine dose and duration of use when iodine is ingested in excess of the recommended daily dietary amount. The major health effect of concern with excess...

The aim of the present study was to examine the effects of different doses of recombinant human growth hormone (rhGH) on children with growth hormone deficiency (GHD) and on thyroid and glucose metabolism to identify more reasonable therapeutic doses of growth hormone (GH) for the treatment of this condition. In total, 60 prepubertal patients with GHD were randomly divided into the high-dose an...

BACKGROUND Trauma patients often require multiple imaging tests, including computed tomography (CT) scans. CT scanning, however, is associated with high-radiation doses. The purpose of this study was to measure the radiation doses trauma patients receive from diagnostic imaging. METHODS A prospective cohort study was conducted from June 1, 2004 to March 31, 2005 at a Level I trauma center in ...

Introduction: Trace elements are important for the normal function of thyroid and prevention of its diseases. Normal activities of thyroid including the synthesis of thyroid hormones and regulation of metabolism are dependent on the presence of trace elements. On the other hand, thyroid hormones may also affect the trace element levels. In this study, we investigated the effects of induced hype...

In some countries, in order to perform rhTSH-aided thyroid remnant ablation (TRA) after surgery, it is generally necessary to confirm that thyroidectomy has been almost complete. Otherwise, the nuclear medicine specialist will not administer a high radioiodine dose because it might be hazardous due to the possibility of thyroid remnant actinic thyroiditis. Considering this, it would be necessar...

esophageal cancer is the eighth most ordinary cancer and the sixth most common cancer between the males and ninth for females in the world; its major and effective treatment is external radiotherapy. this type of cancer can be found in different areas of esophagus including cervical, upper, middle and lower esophagus. in this treatment, healthy tissues such as the trachea, spine and sternum and...

Introduction: This is a prospective study of patients treated for a solitary toxic nodule with a fixed dose of radioiodine ( I) and followed for at least 1 year in Mashhad, north east of Iran. 131 Methods: We evaluated 780 patients who presented to the university hospital of Ghaem during a 7-year period because they had at least one thyroid nodule. We found hot thyroid nodules in 95 (12%) patie...

BACKGROUND Administration of diagnostic activities of 131I, performed in order to detect thyroid remnants after surgery and/or thyroid cancer recurrence/metastases, may lead to reduction of iodine uptake. This phenomenon is called "thyroid stunning". We estimated radiation absorbed dose-dependent changes in genetic material, in particular in sodium iodide symporter (NIS) gene promoter, and NIS ...

Thyroid gland explant cultures from prometamorphic Xenopus laevis tadpoles were evaluated for their utility in assessing chemicals for thyroid hormone (TH) synthesis disruption. The response of cultured thyroid glands to bovine thyroid stimulating hormone (bTSH) and the TH synthesis inhibitors methimazole, 6-propylthiouracil, and perchlorate was determined. Thyroid glands continuously exposed f...