We present a high-speed transport-of-intensity equation (TIE) quantitative phase microscopy technique, named TL-TIE, by combining an electrically tunable lens with a conventional transmission microscope. This permits the specimen at different focus position to be imaged in rapid succession, with constant magnification and no physically moving parts. The simplified image stack collection signifi...

This article presents an intelligent social grouping service for identifying right participants to support CSCW and CSCL. We construct a three-layer hierarchical social network, in which we identify two important relationship ties – a knowledge relationship tie and a social relationship tie. We use these relationship ties as metric to measure the collaboration strength between pairs of particip...

Previous research has shown that spending money on others (prosocial spending) increases happiness. But, do the happiness gains depend on who the money is spent on? Sociologists have distinguished between strong ties with close friends and family and weak ties--relationships characterized by less frequent contact, lower emotional intensity, and limited intimacy. We randomly assigned participant...

Exploring the structural topology of genome-based large-scale metabolic network is essential for investigating possible relations between structure and functionality. Visualization would be helpful for obtaining immediate information about structural organization. In this work, metabolic networks of 75 organisms were investigated from a topological point of view. A spread bow-tie model was prop...

Whole-sediment toxicity identification and evaluation (WS-TIE) is a relatively new approach for assessing the cause of toxic effects to benthic organisms in sediments. Akin to aqueous TIE methods, the premise of the WS-TIE method is that the chemical toxicant(s) responsible for observed effects can be identified through a series of treatments that are designed to reduce the bioavailability and,...

Triple immunofluorescence staining has recently been developed to simultaneously identify all muscle fibers on a single cryosection which is helpful for clinical and basic research, but it has disadvantages such as fast photobleaching and unclear outlines of muscle fibers. Triple immunoenzyme staining (TIE) is likely to avoid these disadvantages. In this study, we aimed to establish a sensitive...

A synthetic 7-mer, HHHRHSF, was recently identified by screening a phage display library for binding to the Tie-2 receptor. A polyethylene-oxide clustered version of this peptide, termed vasculotide (VT), was reported to activate Tie-2 and promote angiogenesis in a mouse model of diabetic ulcer. We hypothesized that VT administration would defend endothelial barrier function against sepsis-asso...

Building on existing stochastic actor-oriented models for panel data, we employ a conditional logistic framework to explore growth mechanisms for tie creation in continuously-observed networks. This framework models the likelihood of tie formation distinguishing it from hazard models that consider time to tie formation. It enables multiple growth mechanisms for network evolution (homophily, foc...

10 REVIEW OF THE LITERATURE 12 1. The VEGF family 12 1.1. Growth factors 1.1.1. Vascular endothelial groth factor (VEGF-A) 12 1.1.2. VEGF-B 13 1.1.3. VEGF-C 13 1.1.4. VEGF-D 15 1.1.5. VEGF-E 16 1.2. The VEGF receptors 16 1.2.1. VEGFR-1 (or FLT1) 17 1.2.2. VEGFR-2 (KDR) 17 1.2.3. NEUROPILIN-1 (or receptor for VEGF165) 17 1.2.4. VEGFR-3 (or Flt4) 19 2. The Angiopoietin/Tie family 19 2.1. Growth f...

School districts that implement stable matchings face various decisions that affect students’ assignments to schools. We study properties of the rank distribution of students with random preferences when schools use different tie-breaking rules to rank equivalent students. Under a single tie-breaking rule, where all schools use the same ranking, a constant fraction of students are assigned to o...