Activating mutations in AVPR2 are associated with nephrogenic syndrome of inappropriate antidiuresis (NSIAD). NSIAD causes hyponatremia, decreased serum osmolality and clinical symptoms, which may present from birth or in infancy and include hypotonia, irritability, vomiting and/or seizures. Symptoms in later life are often less specific and include malaise, dizziness, confusion, tiredness and ...

In recent years, driver drowsiness has been one of the major causes of road accidents and can lead to severe physical injuries, deaths and significant economic losses. Since car accidents may be caused by the driver’s tiredness, there are some assistance systems designed for bringing the attention of a driver. In this paper, we review different measures and discuss its advantages and limitation...

Road accidents, due to the tiredness or the distraction of the drivers, unfortunately became more serious than a war. Although more or less effective solutions were developed to solve this problem, these last remain in general constraining and/or sensitive to the variations of lighting. This paper presents a new approach for analyzing the driver's vigilance based on motion analysis of an o...

Three years into diagnosis she had symptoms of increasing tiredness, breathlessness and tachycardia. An echocardiogram confirmed ventricular dilatation suggesting myocardial involvement. She was recommenced on Cyclophosphamide with Methyprednisolone, and was also commenced on Frusemide and Enalapril which initiated control of her cardiac function. Her ejection fraction improved from 30% to 52%....

What are common symptoms? Trouble falling or staying asleep is usually the main problem. You may have several nights of poor sleep followed by a night of better sleep. Other common symptoms include: • Anxiety/worry • Daytime tiredness • Depression • Difficulty paying attention • Feeling unrested • Forgetfulness • Headaches • Increased errors or accidents • Irritability • Ongoing worries about s...

Twenty-seven-year old male patient reporting tiredness during exercise for three years, after total cavopulmonary connection with extracardiac conduit fenestration and closure with stiches of the free end of right atrioventricular valve (AV) for severe failure in double inlet left ventricle, pulmonary atresia, and aorta arising from rudimentary right ventricle. The patient had undergone right a...

Although insomnia or excessive tiredness are familiar to most who live with schizophrenia they are not unique to it. At least 70% of people suffer from some sleep abnormalities at some point in their lives for various reasons. Sleep problems can be the result of either a physical, mental or emotional issue that disturbs the normal rhythm of our bodies which then creates a vicious circle, as lac...

Personality traits describe how people typically think, feel, and behave. states behave in a given moment. In their daily lives, often the way they do (they enact trait-congruent personality states), but occasionally differently from (trait-incongruent states). Several theories propose that such incongruent should be associated with undesirable outcomes as less positive affect or more tiredness...