نتایج جستجو برای: tnf alpha 308
تعداد نتایج: 247427 فیلتر نتایج به سال:
The objective of this study was to assess whether clinical measures of rheumatoid arthritis activity and severity were influenced by tumor necrosis factor-alpha (TNF-alpha) promoter genotype/haplotype markers. Each patient's disease activity was assessed by the disease activity score using 28 joint counts (DAS28) and functional capacity by the Health Assessment Questionnaire (HAQ) score. System...
Type 1 diabetes mellitus (TIDM) is an autoimmune disease characterized by the destruction of pancreatic p cells. Tumor necrosis factor (TNF) is a pleotropic cytokine with potent immunomodulatory and inflammatory activity. Association studies of TNF polymorphisms and type 1 diabetes (TIDM) frequently demonstrated TNF involvement with TIDM. Although TNF may play an important role in the pathogene...
many species of tea (camellia sinensis) and cowslip (echium amoenum) are used in iranian traditional medicine. the aim of this study was to conduct the survey on the ability of iranian black tea and cowslip extracts on secretion of tumor necrosis factor-alpha (tnf-alpha) by non-infected and infected mouse macrophages. a macrophage infection model with legionella pneumophila and enzyme linked im...
Objective(s): Non- Hodgkin lymphoma (NHL) and acute lymphoblastic leukemia (ALL) are two main hematological malignances which have been driven from lymphoid tissue. Genetic polymorphisms in tumor necrosis factor-α (TNF-α) -308 and lymphotoxin-α (LT-α) +252 may affect their transcription and expression which leads to their high plasma level. The frequency of the TNF-α (-308) and LT-...
Abstract Background: According to increasing prevalence of myocardial infarction (MI) and importance of detecting inflammatory markers, and also controversies in this topic, this trial was performed in Taleghani hospital to define the role of TNF-alpha in patients with myocardial infarction during 2010-2011. Materials and methods: This case-control study was done on patient with definite di...
BACKGROUND The -308 G/A polymorphism in the tumor necrosis factor (TNF) gene has been implicated in the risk of acne vulgaris, but the results are inconclusive. The present meta-analysis aimed to investigate the overall association between the -308 G/A polymorphism and acne vulgaris risk. METHODS We searched in Pubmed, Embase, Web of Science and CNKI for studies evaluating the association bet...
مقدمه: تأثیرات گلیسمیک اوپیوئیدها در انسان و مدل های حیوانی و نیز نقش اوپیوئیدهای اندوژن در سبب شناسی چاقی مورد بحث است. در این مطالعه برای اولین بار به اثر اوپیوئیدها بر لپتین و tnf-alpha مترشحه از ادیپوسیت ها که در علت شناسی چاقی و مقاومت به انسولین نقش مهمی دارند، پرداخته شده است. مواد و روش ها: به مدت 18 هفته 30 رات رژیم غذایی پر انرژی و 10 رات به عنوان شاهد اول رژیم معمول تغذیه جوندگان را...
Generalized aggressive periodontitis (GAP) comprises a group of periodontal diseases characterized by the rapid destruction of periodontal tissues which affect young individuals who generally present no systemic disorders. Polymorphisms in the interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) genes have been associated with an increased severity of chronic periodontitis. The obje...
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