The chemical methods for estimation of vitamin E, recommended in the literature, are all based on the oxidation ofa hydroquinone nucleus which is present in all modifications of tocopherol. This nucleus can either be oxidized in such a way as to give a coloured product, or its reducing power may be measured and hence the quantity of tocopherol calculated. The latter principle is employed in the...

For better stability, vitamin E is commonly used as the non-active esterified pro-drug. Such esters are postulated to be hydrolyzed to the free active form by skin-related esterases. So far, successful conversion of esterified vitamin E to free vitamin E (tocopherol) has been mainly delineated from observed biological effects. Quantitative evidence in human skin is poor. In vitro and in vivo st...

Fast-growing broiler chicks are susceptible to Se deficiency diseases including exudative diathesis (ED). Our objective was to determine if ED could be induced by feeding a current, practical diet and if the incidence was related to selenogenome expression in liver and muscle of chicks. Four groups of day-old broiler chicks (n = 60/group) were fed a corn-soy basal diet (BD; 14 μg Se/kg; produce...

the objective of present study was to investigate the effects of aqueous garlic extracts, vitamin e and n-acetylcysteine on lead-induced lipid peroxidation, changes in antioxidant defense system and semen quality in the rat testes. twenty-five male rats were divided into five groups. animals within different treatment groups were maintained on their respective diets for 35 days as follows: grou...

OBJECTIVES We examined the effects of oral administration of vitamin E, an antioxidant, on endothelium-dependent vasodilation in patients with coronary spastic angina. BACKGROUND We have recently reported that endothelium-dependent vasodilation is impaired in patients with coronary spastic angina (CSA). Furthermore, it is known that oxidative stress may play an important role in the impairmen...