OBJECTIVES The aim of this study was to evaluate how imaging parameters at clinical dental CBCT affect the accuracy in quantifying trabecular bone structures, contrast-to-noise ratio (CNR) and radiation dose. METHODS 15 radius samples were examined using CBCT (Accuitomo FPD; J. Morita Mfg., Kyoto, Japan). Nine imaging protocols were used, differing in current, voltage, rotation degree, voxel ...

PURPOSE To compare the effect of vitamin K(2) and risedronate on trabecular bone in glucocorticoid (GC)-treated rats. MATERIALS AND METHODS Forty-eight Sprague-Dawley female rats, 3 months of age, were randomized by the stratified weight method into 5 groups according to the following treatment schedule: age-matched control, GC administration, and GC administration with concomitant administra...

PURPOSE To use finite element modeling based on flat-panel volume computed tomography (CT) and bone mineral density (BMD) provided by dual-energy x-ray absorptiometry (DXA) to compare bone failure load, stiffness, and trabecular structure in women with anorexia nervosa (AN) and age-matched normal-weight control subjects. MATERIALS AND METHODS The study was approved by the institutional review...

The mechanical properties of bone tissue are reflected in its micro- and nanostructure as well as in its composition. Numerous studies have compared the elastic mechanical properties of cortical and trabecular bone tissue and concluded that cortical bone tissue is stiffer than trabecular bone tissue. This study compared the progression of microdamage leading to fracture and the related local st...

BACKGROUND This study characterized a novel rabbit model of subchondral bone bruise and investigated the intervening effect of calcitonin. METHODS Bone bruise was implemented via controlled free-fall counterpoise on the medial tibial subchondral bone of 5-month-old New Zealand rabbits, with 3, 2.5, or 2 Joules of energy. Subsequent subchondral bone bruise was characterized via magnetic resona...

The aim of this work is to report the histopathological features of jaw bone in 24 cases of bisphoshonate-related osteonecrosis of the jaw. In all cases, lamellar bone trabeculae were thicker (bone sclerosis), had no osteocytes in the lacunae (bone necrosis), and exhibited a Pagetlike structure with marked signs of bone remodeling and formation of multiple trabecular compartments that were not ...

The trabecular and cortical compartments of bone each contributes to bone strength. Until recently, assessment of trabecular and cortical microstructure has required a bone biopsy. Now, trabecular and cortical microstructure of peripheral bone sites can be determined noninvasively using high-resolution peripheral quantitative computed tomography (HR-pQCT). Studies that have used HR-pQCT to eval...

PURPOSE The study aimed to investigate a relationship between the mineral content of human trabecular bone and parameters determined from compression fatigue tests at stepwise-increasing amplitude. METHODS Mineral content of trabecular bone was estimated comparing density and bone mineral density values. The relationship between the ash density, bone mineral density and factors obtained from ...

PURPOSE To study the presence of hyaluronidase activity in the rabbit trabecular meshwork and its regulation by brimonidine. METHODS A spectrophotometric assay that consists of the assessment of N-acetylhexosamine groups released from hyaluronic acid was used to examine hyaluronidase activity. Cyclic adenosine monophosphate (cAMP) levels were assessed by radioimmunoassay. RESULTS Hyaluronid...

PURPOSE Chronic heavy alcohol consumption is associated with bone density loss and increased fracture risk, while low levels of alcohol consumption have been reported as beneficial in some studies. However, studies relating alcohol consumption to bone geometry, volumetric bone mineral density (vBMD) and bone microarchitecture, as assessed by high-resolution peripheral quantitative computed tomo...