Background: Cementless total hip replacement is the common THR performed in England, Wales, Northern Irelandand the Isle of Man. The Corail stem is the most popular cementless implant and has a ODEP 10A rating. Review ofits performance in the registry identified an increase rate of revision amongst the smaller stem sizes. However, claritywas not provided on the explanation for this finding. We ...

stem cells are undifferentiated self regenerating multi potential cells. there are three types of stem cells categories by the ability to form after cells and correlated with the body’s development process. totipotent: these stem cells can form an entire organism such as fertilized egg. ploripotent: ploripotent cells are those that can form any cell in the body but cannot form an entire organis...

this trial was performed to determine if a continuous low-dose infusion of methylprednisolone is as effective as its bolus of high-dose in reducing inflammatory response. the study was single-center, double-blinded randomized clinical trial and performed in a surgical intensive care unit of an academic hospital. in this study, 72 consecutive patients undergoing elective coronary artery bypass g...

stem cells are the cells having some distinguishing characteristics like longevity, high capacity of self-renewal and differentiation, quiescence and highly error-free proliferation. almost all stem cells have the potential of lineage reprogramming, i.e. inter-conversion of cell lineages. they also have the potential to differentiate into almost all kinds of cells. these cells have been found i...

Introduction To evaluate the expression patterns of cytokeratin (K) 12, 13, and 19 in normal epithelium of the human ocular surface to determine whether K13 could be used as a marker for conjunctival epithelium. Methods: Total RNA was isolated from the human conjunctiva and central cornea. Those transcripts that had threefolds or higher expression levels in the conjunctiva than the cornea wer...

Mo40 low-alloy steels are mostly used to produce industrial components such as crane wheels which are exposed to abrasive wear. However, during working conditions, their wear resistance is reduced after a while due to its low hardness. With increasing abrasive wear, the dimensions of components decrease and they need to be repaired for surface modification. In this regard, hard overlay coatings...

Stem cell self-renewal, commitment and reprogramming rely on a poorly understood coordination of cell cycle progression and execution of cell fate choices. Using existing experimental paradigms, it has not been possible to probe this relationship systematically in live stem cells in vitro or in vivo. Alterations in stem cell cycle kinetics probably occur long before changes in phenotypic marker...