نتایج جستجو برای: tranexamic acid txa

تعداد نتایج: 747645  

Journal: :Spine 2016
Alex Soroceanu Jonathan H Oren Justin S Smith Richard Hostin Christopher I Shaffrey Gregory M Mundis Christopher P Ames Douglas C Burton Shay Bess Munish C Gupta Vedat Deviren Frank J Schwab Virginie Lafage Thomas J Errico

STUDY DESIGN A multicenter, prospective, consecutive database of surgical patients with adult spinal deformity (ASD). OBJECTIVE This study investigated the use of antifibrinolytic (AF) therapy in ASD surgery. SUMMARY OF BACKGROUND DATA AF therapy has been shown to be effective in preventing blood loss in some settings. Its effect on major and minor perioperative complications, blood product...

Journal: :International journal of surgery science 2023

Introduction: Objective: To assess the effectiveness and safety of tranexamic acid in lowering postoperative haemoglobin hematocrit decline, operational time, complications, hospitalisation percutaneous nephrolithotomy patients. Methods: A 40-patient Al-Hilla Teaching Hospital randomised controlled clinical trial ran from January 2020 through July 2022. All ultrasound-guided PCNL patients with ...

Journal: :British Journal of Surgery 2021

Abstract Introduction Tranexamic acid (TXA) is proven to reduce blood loss in several surgical fields, but its use femoral fragility fracture (FFF) management ill defined. This study examined the effect of intraoperative TXA on rate postoperative transfusion following FFF. Method A prospective non-randomized case-control 361 consecutive patients admitted centre with FFFs over a 4-month period w...

Journal: :International Journal of Research in Orthopaedics 2022

<p class="abstract">Tranexamic acid (TXA) has been used successfully in the practice of orthopedics to reduce perioperative blood loss, particularly total hip and knee arthroplasty spine surgery. The use TXA shown potential transfusion rates volumes, hemoglobin change hospital-related costs at various degrees. This review aimed evaluate clinical results intraoperative long bone fracture s...

2018
Anne-Sophie Bouthors Benjamin Hennart Emmanuelle Jeanpierre Anne-Sophie Baptiste Imen Saidi Elodie Simon Damien Lannoy Alain Duhamel Delphine Allorge Sophie Susen

BACKGROUND Postpartum haemorrhage (PPH) is the leading cause of maternal death worldwide. Tranexamic acid (TA), an antifibrinolytic drug, reduces bleeding and transfusion need in major surgery and trauma. In ongoing PPH following vaginal delivery, a high dose of TA decreases PPH volume and duration, as well as maternal morbidity, while early fibrinolysis is inhibited. In a large international t...

Journal: :BMC Musculoskeletal Disorders 2021

Abstract Background Hemarthrosis after anterior cruciate ligament (ACL) reconstruction can create many adverse joint effects. Tranexamic acid (TXA) be used to minimize hemarthrosis and associated pain ACL reconstruction. We aimed compare the efficacies of intravenous (IV) administration intra-articular (IA) injection TXA during for reducing postoperative hemarthrosis. Methods A total 120 patien...

2017
Pei Zhang Jinshan He Yongchao Fang Pengtao Chen Yuan Liang Jingcheng Wang

BACKGROUND Patients undergoing hip fracture surgery frequently require blood transfusion. Tranexamic acid (TXA) has been widely used to decrease blood loss and transfusion rates in joint replacement surgery. Therefore, we conducted a meta-analysis to evaluate efficacy and safety of intravenous TXA administration in patients suffering from hip fractures. METHODS Electronic databases were searc...

Journal: :British journal of clinical pharmacology 2016
Luke S Farrow Toby O Smith George P Ashcroft Phyo K Myint

AIM To systematically examine and quantify the efficacy and safety of tranexamic acid in hip fracture surgery. METHODS A systematic literature search was conducted using Medline, EMBASE, AMED, CiNAHL, and the Cochrane Central Registry of Controlled Trials. Two assessors independently screened search outputs for potentially relevant articles which met the eligibility criteria. The primary outc...

2010
Carla Guerriero John Cairns Sudha Jayaraman Ian Roberts Pablo Perel Haleema Shakur

BACKGROUND The identification of safe and effective alternatives to blood transfusion is a public health priority. In sub-Saharan Africa, blood shortage is a cause of mortality and morbidity. Blood transfusion can also transmit viral infections. Giving tranexamic acid (TXA) to bleeding surgical patients has been shown to reduce both the number of blood transfusions and the volume of blood trans...

2017
Michael M. Neeki Fanglong Dong Jake Toy Reza Vaezazizi Joe Powell Nina Jabourian Alex Jabourian David Wong Richard Vara Kathryn Seiler Troy W. Pennington Chris Yoshida-McMath Shanna Kissel Katharine Schulz-Costello Jamish Mistry Matthew S. Surrusco Karen R. O’Bosky Daved Van Stralen Daniel Ludi Karl Sporer Peter Benson Eugene Kwong Richard Pitts John T. Culhane Rodney Borger

INTRODUCTION The California Prehospital Antifibrinolytic Therapy (Cal-PAT) study seeks to assess the safety and impact on patient mortality of tranexamic acid (TXA) administration in cases of trauma-induced hemorrhagic shock. The current study further aimed to assess the feasibility of prehospital TXA administration by paramedics within the framework of North American emergency medicine standar...

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