Anaplasma phagocytophilum, the causative agent of human granulocytic anaplasmosis, is an obligate intracellular bacterium most commonly acquired from tick bites. High seroprevalence rates in endemic regions suggest that transfusion transmission of A phagocytophilum would be a common event; however, only 2 cases have previously been reported. The exact cause of this discrepancy is not known. Who...

Acquired immune deficiency syndrome or acquired immunodeficiency syndrome (AIDS) is a disease of the human immune system caused by the human immunodeficiency virus (HIV). This condition progressively reduces the effectiveness of the immune system and leaves individuals susceptible to opportunistic infections and tumors. HIV is transmitted through direct contact of a mucous membrane or the blood...

The reported IgG seroprevalence against hepatitis E virus (HEV) in German blood donations is 6.8%, and HEV RNA detected in 0.08%, but documented evidence for HEV transmission is lacking. We identified two donations from a single donor containing 120 IU HEV RNA/mL plasma and 490 IU/mL. An infectious dose of 7,056 IU HEV RNA was transmitted via apheresis platelets to an immunosuppressed patient w...

One of the largest therapeutic problem during the continuous treatment of the patients with Hemophilia A and B, are viral infections as Hepatitis B and C, and HIV, and the other infective diseases, which can be transmitted by the transfusion of blood products. The aim of this study is to analyze the complications of the hemophiliacs in Kosovo which have been treated with fresh frozen plasma, cr...

background and aims: torque teno virus (ttv) is a dna virus that isolated from the serum of a japanese patient without a-g transfusion-transmitted hepatitis and other etiology. ttv is detectable in plasma and peripheral blood mononuclear cells, different body fluids and secretions such as stools, saliva, semen, vaginal fluid. the genome exhibits high diversity that has enabled the determination...

conclusions based on our results, it seems that there were no cases of obi among chronic hcv-infected patients with thalassemia and bleeding disorders, particularly hemophilia. however, to improve decisions concerning obi screening, especially in transfusion centers, and concerning the use of comprehensive screening methods, more original studies with more precise laboratory techniques and larg...

to construct a semen bank, the collection of donated semen has to be done and an important concern is the safety of collected semen. the contamination is a big problem. basically, the infectious pathogens can exist within donated semen, hence, a good donor screening is very important. although viruses have an indirect role in sperm quality, but the evidence in banked semen is presently lack. th...

In the developing countries of the world, few people with hemophilia receive adequate care. Nevertheless, Brazil has made significant advances in the treatment of hemophilia over the last decade. The provision of factor concentrates imported by the Government of Brazil is gradually increasing, and patients receive the concentrates for free. A national register was established as well as a coord...

Zika virus (ZIKV), an emerging flavivirus, was initially isolated in 1947 from a Rhesus monkey in Uganda. The first evidence of human transmission of ZIKV was reported in 1952.1 Only sporadic cases of ZIKV in humans were reported in Africa and Asia before 2007, when significant outbreaks were registered outside these regions – on the islands of Micronesia, French Polynesia and New Caledonia in ...