The study examines the level of manifestation heterosis effect in hybrid populations, which increases efciency selection process winter wheat based on number grains main ear. 30 combinations were created using a complete diallel crossings scheme for six varieties soft with wheat-rye translocations (WRT): 1AL.1RS – Ekspromt, Zolotokolosa, Kolumbiia and 1BL.1RS Kalynova, Svitanok Myronivskyi, Leh...

The immunopotentiating activity of neisserial porins, the major outer membrane protein of the pathogenic Neisseria, is mediated by its ability to stimulate B cells and up-regulate the surface expression of B7-2. This ability is dependent on MyD88 and Toll-like receptor (TLR)2 expression, as demonstrated by a lack of a response by B cells from MyD88 or TLR2 knockout mice to the porins. Using pre...

The ability of cone photoreceptors to adapt to light is extraordinary. In this study we evaluated two biochemical processes, visual pigment phosphorylation and transducin translocation, for their ability to contribute to light adaptation in zebrafish cones. Since cytoplasmic Ca2+ regulates light adaptation, the sensitivities of these processes to both light and Ca2+ were examined. Cytoplasmic C...

Insects, the largest group of animals on the earth, owe their prosperity to their ability of flight and small body sizes. The ability of flight provided means for rapid translocation. The small body size allowed access to unutilized niches. By acquiring both features, however, insects faced a new problem: They were forced to beat their wings at enormous frequencies. Insects have overcome this p...

The genetic determinants that confer upon Salmonella the ability to enter non-phagocytic cells are largely encoded in a pathogenicity island located at centisome 63 of the bacterial chromosome. Molecular genetic analysis has revealed that this region encodes a specialized protein secretion system that mediates the export and/or translocation of putative signaling proteins into the host cell. Th...

We have investigated the effect of different maturation stimuli on the ability of mature dendritic cells (DCs) to cross-present newly acquired particulate antigens. Cross-presentation was impaired in DCs matured by treatment with TNF-α, CpG and LPS, but was less affected upon CD40L-induced maturation. The difference could not be explained by decreased antigen uptake or translocation into the cy...

AbstractChromosomal translocations constitute one of the most important, yet uncommon, causes of primary amenorrhea and gonadal dysgenesis. Although X-autosome translocations are frequently associated with streak gonads and clinical features of the Turner syndrome, the majority of X-autosome carriers may present with a variable phenotype, developmental delay, and recognizable X-linked syndrome ...

Temporal changes in electrical resistance of a nanopore sensor caused by translocating target analytes are recorded as sequence pulses on current traces. Prevalent algorithms for feature extraction pulse-like signals lack objectivity because empirical amplitude thresholds user-defined to single out the from noisy background. Here, we use deep learning based bi-path network (B-Net). After traini...