Efficacy of AutologousMelanocyte Transplantation onAmnioticMembrane in PatientsWith Stable Leukoderma: A Randomized Clinical Trial Vitiligo is adisfiguringdiseasewithnodefinitive treatmentoptions that significantlyaffectspatients’qualityof life.Weaimed to compare, forwhatwebelieve to be the first time, the repigmentationefficacyof culturedepidermal cell suspension (CES) and amniotic membrane (A...

Introduction: Vitiligo is a specific, common, often heritable acquired disorder characterized by well-circumscribed milky white cutaneous macules and patches devoid of identifiable melanocyte. Treatment vitiligo, though quite frustrating, includes repigmentation therapies like Topical glucocorticoids, calcipotrieinene, PUVA (Psoralen + Ultraviolet Light A). The combination calcipotriol proves e...

The speaker gave a brief review of published reports on the medical therapy of vitiligo in the last five years. First of all, the use of topical agents was discussed. Fifty percent of the patients had more than 75% of their lesions repigmented after 0.1% tacrolimus treatment. The efficacy was comparable to clobetasol propionate. There was limited data on pimecrolimus but a trial showed that its...

Although the outcomes of various treatment modalities for vitiligo have been studied extensively, the influence of the participant's characteristics on treatment response has not been thoroughly investigated. Therefore, we retrospectively investigated treatment effects and their association with clinical characteristics in Japanese patients with vitiligo. The charts of patients with vitiligo tr...

Vitiligo is the most common acquired skin depigmentation disorder characterized by progressive loss of pigmentation caused destruction functional melanocytes in epidermis. The pathogenesis consists interaction genetic components, metabolic factors associated with cellular oxidative stress, adhesion to epithelium and autoimmunity, which culminate aggression against melanocytes. To date, treatmen...

OBJECTIVE Recent in vitro and in vivo studies have shown that the nonsteroidal anti-inflammatory agent, acetylsalicylic acid (ASA) or aspirin has antioxidant properties on various cell lines and tissues. Hence, the aim of the present study is to investigate the effects of ASA at 2 different concentrations (75 and 300 microg/ml) on the proliferative capacities and lipid peroxidation of in vitro ...

BACKGROUND Suction blister grafting is a useful modality of treatment of patients with resistant and stable vitiligo. However, there have been no detailed studies to find out the best donor site for blister formation. METHODS The study was conducted between the period of October 2004 and February 2005 in the dermatology department at a tertiary care center. Nine patients with vitiligo (focal ...

BACKGROUND Several new treatments appear to have higher success rates than previous therapies for the treatment of vitiligo, and targeted phototherapy is an alternative that may prove to be time-efficient and an effective therapeutic option for the management of this condition. OBJECTIVE The aim of this study was to evaluate the efficacy of targeted broadband UVB phototherapy for the treatmen...