BACKGROUND In an attempt to prepare scaffolds with porosity and compressive strength as high as possible, we prepared porous β-tricalcium phosphate (TCP) scaffolds and coated them with regenerative medicine-grade gelatin. The effects of the gelatin coating on the compressive strength and in vivo osteoblast compatibility were investigated. METHODS Porous β-TCP scaffolds were prepared and coate...

Sucrose acetate isobutyrate (SAIB) is a sugar-based carrier. We have previously applied SAIB as a minimally invasive system for the co-delivery of recombinant human bone morphogenetic protein-2 (rhBMP-2) and found synergy when co-delivering zoledronic acid (ZA) and hydroxyapatite (HA) nanoparticles. Alternative bioceramics were investigated in a murine SAIB/rhBMP-2 injection model. Neither beta...

Miller-Galante II total knee arthroplasty (MG II TKA) was performed on 32 knees in 30 patients. On both the femoral and tibial components, the fibre-metal area was plasma-sprayed with hydroxyapatite-tricalcium phosphate (HA-TCP). The clinical and radiographic outcome was evaluated. A mean preoperative knee score of 26.0 +/- 18.6 (SD) increased to 97.5 +/- 3.5 and a mean pre-operative functional...

Abstract Bone scaffolds require both good bioactivity and mechanical properties to keep shape promote bone repair. In this work, T-ZnO w enhanced biphasic calcium phosphate (BCP) with triply periodic minimal surface (TPMS)-based double-layer porous structure were fabricated by digital light processing (DLP) high precision. Property of suspension was first discussed obtain better printing qualit...

Abstract Exosomes have attracted increasing attention in tissue regeneration and repair due to their roles intercellular communication. Developing a customized delivery system is key exosome-based regenerative therapeutics. Bioceramics play an important role the immunomodulation of macrophages. Here, three-dimensional (3D) printing was applied construct porous scaffolds with β-tricalcium phosph...

Artificial bone materials that exhibit high biocompatibility have been developed and are being widely used for bone tissue regeneration. However, there are no biomaterials that are minimally invasive and safe. In a previous study, we succeeded in developing honeycomb β-tricalcium phosphate (β-TCP) which has through-and-through holes and is able to mimic the bone microenvironment for bone tissue...

Abstract A major number of studies have demonstrated Beta-tricalcium phosphate (β-TCP) biocompatibility, bioactivity, and osteoconductivity characteristics in bone regeneration. The aim this research was to enhance β-TCP's evaluate its physicochemical properties by argon glow discharge plasma (GDP) surface treatment without modifying surface. Treated β-TCP analyzed scanning electron microscopy ...

Abstract Snail ( Achatina fulica ) is one of the sources duck fodder commonly used by local breeders to meet protein needs poultry farms. However, its shells as a by-product are rarely and just become waste. To overcome this problem, we try utilize waste be source bioceramic. contain lot calcium which can precursor make bioceramics. One bioceramics that has potential tricalcium phosphate (TCP) ...

This study was conducted to evaluate the effects of a 3D-printed resorbable polycaprolactone/poly(lactic-co-glycolic acid)/β-tricalcium phosphate (PCL/PLGA/β-TCP) membrane on bone regeneration and osseointegration in areas surrounding implants and to compare results with those of a non-resorbable titanium mesh membrane. After preparation of PCL/PLGA/β-TCP membranes using extrusion-based 3D prin...

Background. Facial aging is a dynamic process involving both soft tissue and bony structures. Skin atrophy, with loss of tone, elasticity, and distribution of facial fat, coupled with gravity and muscle activity, leads to wrinkling and folds. Purpose. The aim of the study was to evaluate microporous tricalcium phosphate (β-TCP) and autologous platelet gel (APG) mix in mice for oral and maxillof...