The chitosan nanoparticles used widely as a drug delivery systems recently. In the present study the Echis carinataus snake venom loaded chitosan nanoparticles were prepared based on ionic gelation of tripolyphosphate and chitosan. The nanoparticles physicochemical characteristics, stability and biological activity of encapsulated venom were studied. The particles were spherical in shape and th...

In recent years, utilization of chitosan /tripolyphosphate nanoparticles has been considered greatly as protein delivery vehicles. Effects of a variety of factors on final characteristics of nanoparticles have been studied by many investigators. Although, the objective of this study was to achieve smaller chitosan nano carriers via changing fabrication parameters such as pH and temperature and ...

Background: The ethanolic extract of Anredera cordifolia (AC) leaves has previously been investigated to have antibacterial activity against Propionibacterium acnes. An active compound propionibacterium acnes was flavonoid. Objective: This study aimed compare antimicrobial differences between nanoparticles and alone. Method: AC were extracted then formulated into using chitosan as the polymer s...

The objective of this study was the preparation ionically crosslinked 6-mercaptopurine (6-MP) monohydrate microparticles through preparing polyelectrolyte complexes drug and polymers. Polymers such as chitosan, casein, carrageenan were used to prepare microparticles, sodium tripolyphosphate crosslinker. Microparticles characterized for their flow behavior, compressibility, percentage yield, mic...