BACKGROUND It is now well established that a GnRH agonist (GnRHa) ovulation trigger completely prevents ovarian hyperstimulation syndrome. However, early studies, using conventional luteal support, showed inferior clinical results following a GnRHa trigger compared with a conventional hCG trigger in normal responder IVF patients. We here present a novel approach for luteal support after a GnRHa...

OBJECTIVE To evaluate the efficacy of two doses of recombinant (r)LH, 75 IU (recommended) or 37.5 IU, for follicular stimulation and outcomes in a randomized cohort of IVF patients. DESIGN Randomized, prospective analysis. SETTING Private hospital incorporating an established IVF center. PATIENT(S) Women undergoing IVF who had a body mass index >18 or <35 and no abnormal karyotype, anovul...

BACKGROUND The aim of this study was to compare the efficacy of antagonist rescue protocol (replacing GnRH agonist with GnRH antagonist and reducing the dose of gonadotropins) combined with cabergoline versus cabergoline alone in the prevention of ovarian hyperstimulation syndrome (OHSS) in patients pretreated with GnRH agonist long protocol who were at high risk for OHSS. METHODS Two hundred...

The objective: to conduct a comparative analysis of the efficacy and tolerability antigestagens (mifepristone) gonadotropin-releasing hormone agonists (aGnRH) as part adjuvant therapy for prevention recurrence uterine fibroids after conservative myomectomy in women reproductive age.Materials methods. study included 99 patients age (19–42 years old) with myoma. were divided into three groups (n=...

The reversal of congenital hypogonadotropic hypogonadism (CHH) is a relatively recent phenomenon that has gained increasing attention over the past 10 years. Yet to date, only one prospective study has been conducted estimating that 10% (95% confidence interval [CI]: 2%–18%) of cases undergo reversal.1 Other retrospective studies have reported rates in the range of 5%–8%2,3 and a recent study s...

Androgen deprivation therapy (ADT) for prostate carcinoma (PCa) may cause cardiometabolic complications unless intermittent androgen blockade (IAB) is instituted. An 80-year-old caucasian man was diagnosed intermediate grade (Gleason 4 + 3) PCa and was treated with continuous ADT with triptorelin plus bicalutamide. After 6 months of treatment, he experienced an acute myocardial infarction and 1...

Background: To compare the effect of GnRH agonist administration with vaginal progesterone on serum progesterone in Luteal phase in control ovarian hyper stimulation and intrauterine insemination cycles Materials and Methods: In this clinical trial, 242 infertile patients because of UEI (unexplained inferetility candidate for ovarian stimulation and intrauterine insemination reffering to infert...