The tumor growth inhibitory efficacy of the somatostatin structural derivative TT-232 was studied using different routes of administration and treatment schedules in various human tumor models. TT-232, containing a five-residue ring structure, has a strong antitumor activity both in vitro and in vivo. The antineoplastic activity of TT-232 has been found to be associated with the induction of pr...

Abstract Background Interferon (IFN)- ?4, a type III IFN, production is controlled by dinucleotide frameshift variant (rs368234815-dG/TT) within the first exon of IFNL4 gene. Carriers -dG allele but not -TT are able to produce IFN-?4 protein. Patients with hepatitis C virus that do protein have higher rates viral clearance suggesting potential inhibitory role in liver-tropic infections. Methods...

BACKGROUND Primary percutaneous transluminal coronary intervention (PCI) and thrombolytic therapy (TT) are alternative means of achieving reperfusion in patients with acute ST segment elevation myocardial infarction (STEMI). OBJECTIVE To compare the outcomes between both reperfusion strategies. The authors sought to compare in-hospital outcomes after PCI or TT for patients with acute STEMI. ...

Tribulus terrestris L. (TT) is an annual plant of the family Zygophyllaceae that has been used for generations to energize, vitalize, and improve sexual function and physical performance in men. The fruits and roots of TT have been used as a folk medicine for thousands of years in China, India, Sudan, and Pakistan. Numerous bioactive phytochemicals, such as saponins and flavonoids, have been is...

HLA-DR3- and HLA-DRw52-associated functional polymorphism was investigated with selected tetanus toxoid (TT)-specific T cell clones. We have shown earlier that HLA-DR antigens are encoded by two distinct loci, DR beta I and DR beta III. The alloantigenic determinant(s) defined by the serological HLA-DR3 specificity map to the former, while the supratypic HLA-DRw52 determinants map to DR beta II...

Abstract Introduction: In the past years, some groups established methods to use promontory stimulation and subjective responses as a tool for preoperative of cochlea before cochlear implant (CI) surgery by temporary transtympanic needle placed on middle ear. Our research group tested CI candidates when presence auditory nerve could not be confirmed other pre-operative tests analyzed objective ...

Abstract Introduction Hypocalcemia is a frequent complication following thyroidectomy which can delay discharge and increase overall treatment expenditure. We aimed to assess the predictive value of absolute relative intact Parathormone(iPTH) decline levels as reliable markers post-operative hypocalcemia. Method This prospective study included 95 consecutive patients at our tertiary care centre...

One of the restrictions on the use of commercial hydrofoil crafts, which have advantages in comparison with common displacement ships, is the necessity for specialized maintenance of the foil systems. Such work usually requires complicated equipment and experienced specialists. This paper offers a new method effectively restoring of a hydrofoil after foil damage. A simplified method for conserv...