نتایج جستجو برای: tumor angiogenesis
تعداد نتایج: 454475 فیلتر نتایج به سال:
A tumor consists of a population of rapidly dividing and growing cancer cells. Cancer cells have lost their ability to divide in a controlled fashion and as a consequence they rapidly accumulate mutations. In such way cancer cells (or sub-populations of cancer cells within a tumor) will acquire stronger proliferative capacity [1]. Tumors cannot grow beyond a certain size due to a lack of oxygen...
Crucial to designing angiostatic and vascular targeting agents is the identification of target molecules. Because angiogenesis is not limited to pathologic conditions, careful evaluation of putative therapeutic targets is warranted to prevent adverse effects associated with impaired physiologic angiogenesis. To identify tumor-specific angiogenesis markers, we compared transcriptional profiles o...
The expression of the placental growth factor (PGF) in cancer cells and tumor microenvironment can contribute to induction angiogenesis, supporting cell metabolism by ensuring an adequate blood supply. Angiogenesis is a key component as it facilitates delivery nutrients oxygen rapidly growing cells. PGF recognized novel target for anti-cancer treatment due its ability overcome resistance existi...
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