In stage V twin-twin transfusion syndrome (TTTS), up to 50% of surviving twins die or experience permanent disabilities, likely due to acute intertwin hemorrhage resulting in sudden severe anemia of the survivor. Although fetal middle cerebral artery (MCA) Doppler studies demonstrate strong correlation with fetal hemoglobin values, acute hemorrhagic events are more difficult to diagnose, and op...

Fetal erythropoietin (Epo) concentrations were studied in monochorionic (MC) twin pregnancies in relation to twin-twin transfusion syndrome (TTTS). Matched maternal and fetal blood samples in utero were obtained from MC twins with TTTS (n = 15) and without TTTS (n = 6). In a second group of five sets of twin pairs with or without TTTS, immunolocalization of Epo was performed in archived paraffi...

The goal of this study was to assess the characteristics of monochorionic-diamniotic (MD) growth-retarded twin infants with twin-twin transfusion syndrome (TTTS) compared with those without TTTS during the third trimester. Retrospective analyses of the growth patterns and amniotic fluid volumes were performed on 5 MD twin pregnancies in which one or both twins showed growth retardation with TTT...

OBJECTIVE To estimate the odds of severe cerebral injury and long-term neurodevelopmental impairment in monochorionic twins treated with amnioreduction versus laser surgery for twin-twin transfusion syndrome. METHODS A systematic review and meta-analysis of studies on cerebral injury and long-term impairment after amnioreduction versus laser surgery were conducted. Odds ratios (OR) with their...

Background: Neonatal polycythemia is a condition that incidentally encountered in clinical practice. It characterized by elevated hemoglobin levels (above 22 g/dL) and hematocrit ratios above 65%. important to understand both the prevalence as well related risk factors of this untreated preventable can result development hyperviscosity syndromes leading potential multiple organ failure. Prevale...

A monochorionic twin pregnancy is one in which both babies are dependent on a single, shared placenta. Around one-third of twin pregnancies in the UK have monochorionic placentas. Monochorionic placentation can also occur in higher-order multiples. There has been a recent increase in all types of multiple pregnancies with the increasing use of assisted reproductive techniques. Monochorionic (MC...

A monochorionic twin pregnancy is one in which both babies are dependent on a single, shared placenta. Around one-third of twin pregnancies in the UK have monochorionic placentas. Monochorionic placentation can also occur in higher-order multiples. There has been a recent increase in all types of multiple pregnancies with the increasing use of assisted reproductive techniques. Monochorionic (MC...