نتایج جستجو برای: type β

تعداد نتایج: 1494932  

2014
YASUSHI ICHIKAWA YOJI NAGASHIMA KAORI MORIOKA KAZUNORI AKIMOTO YASUYUKI KOJIMA TAKASHI ISHIKAWA AYUMU GOTO NORITOSHI KOBAYASHI KAZUTERU WATANABE MITSUYOSHI OTA SHOICHI FUJII MAYUMI KAWAMATA RYO TAKAGAWA CHIKARA KUNIZAKI HIROKAZU TAKAHASHI ATSUSHI NAKAJIMA SHIN MAEDA HIROSHI SHIMADA YOSHIAKI INAYAMA SHIGEO OHNO ITARU ENDO

Colorectal flat-type tumors include laterally spreading tumors (LSTs) and flat depressed-type tumors. The former of which shows a predominant lateral spreading growth rather than an invasive growth. The present study examined the morphological characteristics of LSTs, in comparison with polypoid- or flat depressed-type tumors, along with the expression of atypical protein kinase C (aPKC) λ/ι, a...

2014
Kyong Yeun Jung Kyoung Min Kim Soo Lim

The goal for the treatment of patients with diabetes has today shifted from merely reducing glucose concentrations to preventing the natural decline in β-cell function and delay the progression of disease. Pancreatic β-cell dysfunction and decreased β-cell mass are crucial in the development of diabetes. The β-cell defects are the main pathogenesis in patients with type 1 diabetes and are assoc...

Journal: :Science 2002
Maciej Lewenstein

1129 of the β-hairpin with the base of the A1 domain is unexpected and may account for the ability of VWD type 2B mutations to increase the binding affinity. The A1 domain contains a compact α/β fold delimited by a single disulfide loop. In the free A1 domain, the sequence extending on the amino-terminal side of the disul-fide bond lies against the α/β surface (8), and this amino-terminal exten...

2013
Quanhai Li Kiyoko Kawamura Shan Yang Shinya Okamoto Hiroshi Kobayashi Yuji Tada Ikuo Sekine Yuichi Takiguchi Masato Shingyouji Koichiro Tatsumi Hideaki Shimada Kenzo Hiroshima Masatoshi Tagawa

Interferons (IFNs) have been tested for the therapeutic effects in various types of malignancy, but mechanisms of the anti-tumors effects and the differential biological activities among IFN members are dependent on respective cell types. In this study, we examined growth inhibitory activities of type I and III IFNs on 5 kinds of human mesothelioma cells bearing wild-type p53 gene, and showed t...

Journal: :Journal of Differential Equations 2022

In this paper we consider a Hartree-Fock type system made by two Schrödinger equations in presence of Coulomb interacting term and cooperative pure power subcritical nonlinearity, driven suitable parameter β≥0. We show the existence semitrivial vectorial ground states solutions depending on parameters involved. The asymptotic behavior with respect to β these is also studied.

2013
Jan Menne Nelli Shushakova Janina Bartels Yulia Kiyan Robert Laudeley Hermann Haller Joon-Keun Park Matthias Meier

Activation of protein kinase C (PKC) has been implicated in the pathogenesis of diabetic nephropathy with proteinuria and peritubular extracellular matrix production. We have previously shown that the PKC isoforms α and β mediate different cellular effects. PKC-β contributes to hyperglycemia-induced renal matrix production, whereby PKC-α is involved in the development of albuminuria. We further...

Journal: :Journal of Inequalities and Applications 2022

Abstract The coupled fractional Fourier transform $\mathcal {F}_{\alpha ,\beta}$ Fα,β is a two-dimensional depending on two angles α and β , which are in such way that the parameters $\gamma =(\alpha +\beta )/2$ xmlns:m...

Journal: :Chemical Engineering Journal 2022

Owing to high interfacial conductivity, organic heterostructures hold great promises augment the electrical performances of electronic devices. In this endeavor, present work reports fabrication novel polyporphine/phthalocyanine and investigates modulation charge transport induced by structural change polyporphine its implication on ammonia sensing properties. Polyporphines materials are electr...

2011
Fang Zhao Qinghua Wang

Type 1 and type 2 diabetes are characterized by an excessive loss of insulin producing β-cells. β-cells are particularly susceptible to increased oxidative stress induced apoptosis due to low expression of major antioxidants. Peroxiredoxin-2 (PRDX2) belongs to a group of antioxidants with antiapoptotic roles. Preliminary data indicate PRDX2 is expressed in the β-cells. Endogenous PRDX2 in the β...

2008
V. Nikiforov R. H. Schelp

We prove a number of Turán and Ramsey type stability results for cycles, in particular, the following one: Let n ≥ 4, 0 < β ≤ 1/2 − 1/2n, and the edges of K ⌊(2−β)n⌋ be 2-colored so that no mononchromatic C n exists. Then, for some q ∈ ((1 − β) n − 1, n) , we may drop a vertex v so that in K ⌊(2−β)n⌋ − v one of the colors induces K q,⌊(2−β)n⌋−q−1 , while the other one induces K q ∪ K ⌊(2−β)n⌋−q...

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