Diabetes mellitus type 1 (T1D) develops as a result of the interaction genetic and environmental factors. Genetic predisposition to T1D turns into clinical reality only in half hereditary cases, which indirectly indicates importance external factors, significance is periodically reviewed. Retrospective prospective foreign national studies were included. PubMed, Medline eLibrary searched. Modern...

BACKGROUND Maintainance of a stable basal insulin level is important for glycemic control in treatment of diabetes mellitus. Recently introduced insulin degludec has the longest duration of action among basal insulin formulations. The purpose of this study was to assess changes in quality of life (QOL) associated with switching the basal insulin regimen to degludec in patients with type 1 and t...