Background:The prevalence of diabetes mellitus is increasing worldwide and the relationship between peripheral vascular involvement and the complications of diabetes disease, such as retinopathy, has been reported in some studies but has not yet been fully proven. The aim of this study was to investigate the relationship between diabetes complications and peripheral and central vascular involve...

Abstract Diabetes mellitus is one of the major metabolic disorders. Diabetes is recognized for severe complications including diabetic nephropathy, neuropathy and retinopathy. Long-lasting effect of hyperglycemia results in increased oxidative stress. Oxidative stress results from an imbalance between radical-generating and radical scavenging systems. Increased oxidative stress has been shown ...

The 2016 Diabetes Care Editors’ Expert Forumon thepreventionof type2diabetes is bothwelcome and timely (1). Prevention of type 2 diabetes is not a routine therapeutic goal in clinical practice despite the1) increasing prevalence of type 2 diabetes, 2) large numbers of at-risk individuals with prediabetes and/or metabolic syndrome, and 3) presence of interventions for effective disease preventio...

Background: Diabetes mellitus is an endocrine disorder of carbohydrate metabolism resulting primarily from inadequate insulin release (type I) or insulin insensitivity coupled with inadequate compensatory insulin release (type II). Oxidative stress is one of the complications of diabetes that increases in both types of diabetes and treatment with antioxidants can reduce the complications of dia...

Abstract Background: Diabetes mellitus is a chronic disorder characterized by impaired metabolism of glucose and lipids due to defect in insulin secretion or action. The association obesity with development type 2 diabetes may be partly mediated altered adipokines adipose tissues which contribute obesity. It has been reported that reduction plasma adiponectin level related the elevation resista...