Near-critical and supercritical fluids have been used successfully in the manufacture of vaccine, antibody and antibiotic microparticles by Carbon-dioxide Assisted Nebulization with a Bubble Dryer ® (CAN-BD). In CAN-BD two fluid streams, a drug, antibody, or vaccine solution or suspension, and supercritical or near-critical CO2, are intimately mixed in a low dead volume tee. These mixed fluid s...

Introduction We propose a new variant of smoothed aggregation (SA) suitable for nonsymmetric linear systems. SA is a highly successful and popular algebraic multigrid method for symmetric positive-definite systems [3, 2]. A relatively large number of significant parallel smoothed aggregation codes have been developed at universities, companies, and laboratories. Many of these codes are quite so...

Endobronchial lung volume reduction (ELVR) may be helpful in a selected group of patients with advanced stages of emphysema. However, collateral ventilation (CV) from adjacent lobes through collateral channels often prevents target lobe atelectasis, which presumably mediates clinical responses after ELVR. With the goal of identifying patients who are more or less likely to benefit, we propose e...

The anterior cruciate ligament (ACL) of the knee and the function of its anteromedial (AM) and posterolateral (PL) bundles are a focus of orthopedic research. Because of the probability that third-year and fourth-year osteopathic medical students will encounter ACL injuries during clinical rotations, it is of paramount importance that students fully understand the functions of the AM and PL bun...

statement of problem: chondrosarcoma is a tumor which includes 10 percent of the bone primary tumors. its prevalence is half of the osteosarcoma and two times of ewing’s. the mean age of the patients ranges between 30-50 years of old. there is no significant sex or race predilection. the most common complaint is the presence of a painless and enlarging mass. its clinical course is described as ...

background and objectives: type 2 diabetes is the most prevalent form of diabetes mellitus and is associated with a variety of complications. homocysteine is an important independent risk factor for atherosclerotic diseases in both diabetic and non diabetic subjects. the association between these two is still unclear. the aim of this study was to assess the serum homocysteine levels in uncompli...

metabolic syndrome and its pathological sequel, type 2 diabetes are considered as important global health problems. metformin is the most common drug prescribed for patients with this disorder. consequently, understanding the genetic pathways involved in pharmacokinetics and pharmacodynamics of this drug can have a considerable effect on the personalized treatment of type 2 diabetes. in this st...

background : joint proprioception plays an important role in limb movement and awareness of position sense. diabetes has a lot of complications such as lossof sensoryfunction, which canleadtoimpaired balance, thus the aim of this study to evaluated joint proprioception and balance in diabetic patients. methods: twenty type ii diabetic patients and20healthy controls participated in this case-con...