breast cancer is one of the most common malignancies among women. although chemotherapy remains a major therapeutic approach to treat cancers, drug therapy often fails for several reasons, particularly the drug resistance. resistance to multiple chemotherapeutic agents is one of the most important problems in the treatment of different types of cancers. therefore, in this study a resistant sub ...

       The purpose of this review article is to characterize all of the parameters regarding the types, polymers used, and release kinetics of matrix tablets. Matrix system was the earliest oral extended release platform for medicinal use. Matrix tablets are most commonly used methods to modulate the release profile of drugs. They are much desirable and preferred for such therapy because they o...

enterococci are gram positive and catalase- negative cocci that are found in the gastrointestinal tract of mammals and birds, and are readily isolated from soil, surface and waters. the aim of this study was to discriminate between enterococcus isolates based on repetitive element sequence based –pcr (rep-pcr) with the boxa2r primer and their antibiotics profile. enterococci isolates were obtai...

drug abuse is considered as the most common poisoning in the world. stimulants agent especially amphetamines and methamphetamines are among important abused substances. different types of neurologic, psychiatric, respiratory, gastrointestinal, and cardiogenic complications have been reported to be related to methamphetamine consumption. some of these substances could cause dysrhythmias which is...

background drug abuse is a disorder associated with unhealthy pattern of drug consumption and is a widespread social delinquent both in society and at home. there have only been a few studies conducted on the frequency and types of harmful behaviors among drug abusers. objectives the objective of this study is to investigate the frequency of harmful behaviors in people who are suffering from dr...

to evaluate off-label and off-nccn guidelines uses of antineoplastic drugs in a major chinese hospital.totally 1122 patients were selected from july to december 2011. then, the off-label and off-nccn guidelines uses of antineoplastic drugs were analyzed.in 798 of 1122 patients (71.12%), drugs were used for off-label. in 317 of 1122 patients (28.25%), the drugs were prescribed for off-label and ...