نتایج جستجو برای: ubiquinol

تعداد نتایج: 659  

2015
Hashime Sawai Takako Takai-Igarashi Hiroshi Tanaka

UNLABELLED Bipolar disorder (BD) is a psychiatric disease considered to polygenic with multiple factors in genetics, each of which is not dominant but collaborative during pathogenic progression. We describe a method that estimates the collaborative contribution to the disease between a certain well-studied pathway and the other candidate pathway using Gene Set Enrichment Analysis (GSEA). We de...

Journal: :The Journal of biological chemistry 1992
K Mukai S Itoh H Morimoto

A kinetic study of the regeneration reaction of vitamin E (tocopherol) with eight biological hydroquinones (HQs) (ubiquinol-10 (Q10H2 1); ubiquinol-0 (Q0H2 2); vitamin K1 HQ (VK1H2 3); vitamin K3 HQ (VK3H2 4); alpha-, beta-, and gamma-tocopherol-HQs (alpha-, beta-, and gamma-TQH2 5-7); and 2,3,5-trimethyl-1,4-HQ (TMQH2 8)) in solution was performed. The second-order rate constants (k4) for the ...

2001
Hitoshi Morimoto

A kinetic study of the regeneration reaction of vitamin E (tocopherol) with eight biological hydroquinones (HQs) (ubiquinol-10 (QloH2 1); ubiquinol-0 (QoH2 2); vitamin K1 HQ (VKIH2 3); vitamin Kg HQ (VKSHZ 4); a-, 8-, and y-tocopherol-HQs (a-, B-, and r-TQH2 B-z); and 2,3,5-trimethyl-1,4-HQ (TMQH2 S)) in solution was performed. The second-order rate constants (k4) for the reaction of HQs 1-S wi...

Journal: :Stroke 2001
M C Polidori P Mecocci B Frei

BACKGROUND AND PURPOSE Free radical hyperproduction may play an important role in brain hemorrhage and ischemia/reperfusion injury. The aims of this study were to assess whether antioxidant depletion occurs after intracranial hemorrhage (ICH) and head trauma (HT) and to evaluate the relation between the diameter of the brain lesion, the degree of the neurological impairment, and any observed an...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Tomoo Shiba Yasutoshi Kido Kimitoshi Sakamoto Daniel Ken Inaoka Chiaki Tsuge Ryoko Tatsumi Gen Takahashi Emmanuel Oluwadare Balogun Takeshi Nara Takashi Aoki Teruki Honma Akiko Tanaka Masayuki Inoue Shigeru Matsuoka Hiroyuki Saimoto Anthony L Moore Shigeharu Harada Kiyoshi Kita

In addition to haem copper oxidases, all higher plants, some algae, yeasts, molds, metazoans, and pathogenic microorganisms such as Trypanosoma brucei contain an additional terminal oxidase, the cyanide-insensitive alternative oxidase (AOX). AOX is a diiron carboxylate protein that catalyzes the four-electron reduction of dioxygen to water by ubiquinol. In T. brucei, a parasite that causes huma...

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