نتایج جستجو برای: ulcerative atherosclerotic plaque
تعداد نتایج: 70932 فیلتر نتایج به سال:
Atherosclerotic alterations of the internal carotid artery frequently result in ischemic stroke. However, it remains unclear which specific factor mainly causes an increased risk of stroke. Constant improvements of the diagnostic possibilities of ultrasonic examinations provide increasingly profound insight into plaque alterations. If "risk plaque" could be reliably identified, the therapeutic ...
See related article, pages 2507–2516 Atherosclerosis remains a major cause of death in industrialized countries. Our understanding of the natural course of the disease and of the effects of intervention is mainly based on autopsy studies and on studies in animal models. This has primarily been because of the lack of good tools to image plaque components in vivo. Indeed, even in animal studies, ...
Carotid atherosclerotic stenosis is a risk factor for ischemic stroke. The rapid development of neuroimaging techniques had led to carotid angioplasty with stenting (CAS) becoming a useful, effective and minimally invasive method for the treatment of extracranial carotid artery stenosis. The aim of the present study was to identify independent risk factors to predict perioperative major adverse...
Atherectomy is a procedure which is performed to remove atherosclerotic plaque from diseased arteries. Atherosclerotic plaques are localized in either coronary or peripheral arterial vasculature and may have different characteristics depending on the texture of the plaque. Atherectomy has been used effectively in treatment of both coronary and peripheral arterial disease. Atherectomy devices ar...
See related article, pages 2507–2516 Atherosclerosis remains a major cause of death in industrialized countries. Our understanding of the natural course of the disease and of the effects of intervention is mainly based on autopsy studies and on studies in animal models. This has primarily been because of the lack of good tools to image plaque components in vivo. Indeed, even in animal studies, ...
Atherosclerotic plaque destabilization and rupture leads to acute coronary syndromes which cause serious damage to human health worldwide. However, there is currently a lack of efficient therapeutic methods. Mammalian target of rapamycin (mTOR) has been suggested to be involved in the development of atherosclerotic plaques and serves as a therapeutic target. The present study was performed to d...
After a period of relative senescence in the field of vascular smooth muscle cell (VSMC) research with particular regards to atherosclerosis, the last few years has witnessed a resurgence, with extensive research re-assessing potential molecular mechanisms and pathways that modulate VSMC behaviour within the atherosclerotic-prone vessel wall and the atherosclerotic plaque itself. Attention has ...
Inflammation is a key feature of atherosclerosis and a target for therapy. Statins have potent anti-inflammatory properties but these cannot be fully exploited with oral statin therapy due to low systemic bioavailability. Here we present an injectable reconstituted high-density lipoprotein (rHDL) nanoparticle carrier vehicle that delivers statins to atherosclerotic plaques. We demonstrate the a...
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