We agree with Patricia Izurieta and colleagues that the high disease incidence observed in Belgium might result more pronounced epidemiological changes, whereas these changes be less apparent countries a lower reported of invasive pneumococcal disease. This fact can well illustrated by comparing evolution serotype replacement England Wales after introduction 13-valent conjugate vaccine (PCV13)....

Abstract Background Disruptive behaviors, including agitation, disinhibition, irritability, and aberrant motor are commonly observed in patients with Alzheimer's disease (AD). However, the neuroanatomical basis of these disruptive behaviors is not fully understood. Objective To confirm differences cortical thickness surface area between AD healthy controls to further investigate features associ...