A recent study has reported that the application of thermal energy delivered through a bronchoscope (bronchial thermoplasty) impairs the ability of airway smooth muscle to shorten in response to methacholine (MCh)(Danek CJ, Lombard CM, Dungworth DL, Cox PG, Miller JD, Biggs MJ, Keast TM, Loomas BE, Wizeman WJ, Hogg JC, and Leff AR. J Appl Physiol 97: 1946-1953, 2004). If such a technique is suc...

BACKGROUND COPD is characterised by reduced airway lumen dimensions and fewer peripheral airways. Most studies of airway properties sample airways based upon lumen dimension or at random, which may bias comparisons given reduced airway lumen dimensions and number in COPD. We sought to compare central airway wall dimensions on CT in COPD and controls using spatially matched airways, thereby avoi...

background: foreign body aspiration (fba) of tracheobronchial trees is accidental evidence in children. it occurs the most common in less than 3-year age old. diagnosis of inhaled fb is a dilemma in the pediatric, particularly in delayed or missed conditions. the aim of the study assessed the clinical features and rigid bronchoscopic finding of aspirated fb in tracheobronchial trees of children...

Small airways disease includes a spectrum of inflammatory and fibrotic pulmonary diseases centered on the small conducting airways. High-resolution computed tomography plays a key role in the detection and classification of small airways disease and, when combined with relevant clinical and pathologic findings, leads to a more accurate diagnosis. The imaging manifestations of small airways dise...

A collaborative program between the Papua New Guinea (PNG) Institute of Medical Research and the Hunter Mucosal Group has completed studies relevant to protection of the airways against bacterial infection. Specifically, these studies addressed the mucosal capacity to produce local immunoglobulins and the capacity of the airways to respond to an oral vaccine containing inactivated nontypeable H...

Asthma was originally described as an inflammatory disease that predominantly involves the central airways. Pathological and physiological evidence reported during the past few years suggests that the inflammatory process extends beyond the central airways to the peripheral airways and the lung parenchyma. The small airways are capable of producing T-helper-2 cytokines, as well as chemokines, a...

many patients with atopic eczema (ae) would “march” to develop allergic rhinitis (ar) and asthma. physicians, patients and their families often do not appreciate the significance of these diseases as co-morbidities of atopy. the aim of this study was to evaluate the prevalence and severity of airway atopies in patients with ae. ar and asthma severity were assessed in consecutive ae patients see...

This research is mainly to understand the business operation environment internally and externally which correlate with Airline industry. It also aims address various issues that affect development of Kenya airways as an international airline operator. Such relationship airway its host countries essential in determining barriers a harmonious coexistence strategy development. There are company’s...

Physiological morphometry is a critical factor in the flow dynamics in small airways. In this study, we visualized and analyzed the three-dimensional structure of the small airways without dehydration and fixation. We developed a two-step method to visualize small airways in detail by staining the lung tissue with a radiopaque solution and then visualizing the tissue with a cone-beam microfocal...