The European Regulation 536/2014, entered into force on June 16, 2014 and not effective for several years a delay in the development of fully functional portal, has represented turning point legislation regarding clinical trials medicinal products. Unlike other countries, Italy was unable to translate multitude decrees regulating one legislative act.

Climate policy adoption in one country increases the probability of neighbouring countries. Governments can thus support global climate action by adopting a leadership role and do not need to worry about freeriding behaviour.