1. The concentrations of liver glycogen and plasma d-glucose were measured in caesarian-delivered newborn rats at time-intervals up to 3h after delivery after treatment of the neonatal rats with glucagon, dibutyryl cyclic AMP, cortisol or cortisol+dibutyryl cyclic AMP. Glycogenolysis was promoted by glucagon or dibutyryl cyclic AMP in the third hour after birth but not at earlier times. Cortiso...

BACKGROUND Since the Doi Moi reform 1986 economic conditions in Vietnam have changed significantly and positive health and health care developments have been observed. International experience shows that improved economic conditions in a country can reduce the risk of perinatal mortality, decrease the risk of low birth weight and increase the mean birth weight in newborns. The Health and Demogr...

Perinatal asphyxia affects almost all the organs in neonates, kidneys being one of commonly affected organs. Early recognition disturbances renal function is important for early intervention to prevent irreversible damage kidneys. Objective: In this study we observed frequency acute kidney injury (AKI) neonates with clinical staging hypoxemic ischemic encephalopathy (HIE) perinatal asphyxia. Me...

Objective: To determine the frequency of early and late labour induction in premature rupture membranes compare their outcome.
 Study Design: Cross sectional study.
 Place Duration Study: Department Obstetrics & Gynaecology, Combined Military Hospital, Rawalpindi Pakistan,from Jan-Dec 2021.
 Methodology: One hundred sixty-four pregnant women aged 18-35 years, with uncomplicat...

Treating brain tumors using inhibitors of angiogenesis is extensively researched and tested in clinical trials. Although anti-angiogenic treatment holds a great potential for treating primary and secondary brain tumors, no clinical treatment is currently approved for brain tumor patients. One of the main hurdles in treating brain tumors is the blood brain barrier - a protective barrier of the b...

There is an urgent need for new drugs for the chemotherapy of human African trypanosomiasis, Chagas disease and leishmaniasis. Progress has been made in the identification and characterization of novel drug targets for rational chemotherapy and inhibitors of trypanosomatid glycosomal enzymes, trypanothione reductase, ornithine decarboxylase, S-adenosylmethionine decarboxylase, cysteine protease...

Therapeutics delivery into cells has been hurdled due to the barrier of cytoplasmic membrane. Although cell penetrating peptide (CPP) can potentially serve as an intracellular drug delivery vehicle, the application of CPP-based delivery is limited because the unsatisfactory delivery efficiency of CPP conjugated potent cargos is challenging their applications in present. Thus, the development of...

OBJECTIVE To evaluate the reproductive outcome and the mode of delivery in subsequent pregnancies after instrumental vaginal delivery in theatre or caesarean section at full dilatation. DESIGN Prospective cohort study. SETTING Two urban hospitals with a combined total of 10 000 deliveries a year. PARTICIPANTS A cohort of 393 women with term, singleton, cephalic pregnancies who needed oper...

Background: Robson, proposed a new classification system, the Robson’s Ten Group Classification to allow critical analysis of assessing Caesarean section rate according characteristics pregnancy. Auditing Caesarian rates can be done using which in turns helps achieving uniform basis for comparison across centers and various countries. The objective was describe caesarean tertiary care hospital ...