نتایج جستجو برای: urinary proteomics
تعداد نتایج: 137940 فیلتر نتایج به سال:
Proteomics is a leading technology for the high-throughput analysis of proteins on a genome-wide scale. With the completion of genome sequencing projects and the development of analytical methods for protein characterization, proteomics has become a major field of functional genomics. The initial objective of proteomics was the large-scale identification of all protein species in a cell or tiss...
conclusions vur might be more frequent in children with physiological urinary incontinence than the normal population, and might be as common as nmne with intermittent daytime incontinence. results urinary tract infection was found in 23 (34.8%) children, 17 (33.3%) and 6 (40%) patients with nmne and physiological urinary incontinence, respectively. out of 48 patients who underwent vcug, vesico...
4. Newsome BB, Warnock DG, McClellan WM et al. Long-term risk of mortality and end-stage renal disease among the elderly after small increases in serum creatinine level during hospitalization for acute myocardial infarction. Arch Intern Med 2008; 168: 609–616 5. Coca SG, Yusuf B, Shlipak MG et al. Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic rev...
PURPOSE Interstitial cystitis/painful bladder syndrome (IC/PBS) is characterized by chronic pain, pressure and discomfort felt in the pelvis or bladder. An in-depth shotgun proteomics study was carried out to profile the urinary proteome of women with IC/PBS to identify possible specific proteins and networks associated with IC%PBS. MATERIALS AND METHODS Urine samples from ten female IC/PBS p...
Proteomics emerged in the beginning of the 1990s due to the need for new methods for protein analysis. Proteomics is a much newer discipline than genomics, and confronts similar challenges to those that genomics researchers faced in the implementation of large-scale sequencing programs. The definition of proteomics as the use of quantitative protein-level measurements of gene expression to char...
Previous attempts to use urinary protein profiles for diagnostic purposes have been rather disappointing with respect to their clinical validity, in part because of the insufficient reproducibility, sensitivity, and rapidity of available techniques. Therefore, a newly developed, high-throughput technique, namely surface-enhanced laser desorption/ionization (SELDI) ProteinChip array-time of flig...
Novel therapies in autosomal dominant polycystic kidney disease (ADPKD) signal the need for markers of disease progression or response to therapy. This study aimed to identify disease-associated proteins in urinary extracellular vesicles (uEVs), which include exosomes, in patients with ADPKD. We performed quantitative proteomics on uEVs from healthy controls and patients with ADPKD using a labe...
While insulin replacement therapy restores the health and prevents the onset of diabetic complications (DC) for many decades, some T1D patients have elevated hemoglobin A1c values suggesting poor glycemic control, a risk factor of DC. We surveyed the stool microbiome and urinary proteome of a cohort of 220 adolescents and children, half of which had lived with T1D for an average of 7 years and ...
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