BACKGROUND Human leiomyomata (fibroids) are benign tumors of the uterus, represent the most common neoplasms of reproductive-aged women and have a prevalence of ∼70% in the general population. This disorder conveys a significant degree of morbidity and remains the leading indication for hysterectomy in the USA. Prior investigations of aberrant microRNA (miRNA) expression in various malignancies...

Uterine fibroids are benign tumors occurring in 20-50% of women in their reproductive age. They are the most Abstracts of the 12th Royan International Congress on Reproductive Biomedicine frequent indication for hysterectomy at Pre-menopausal age. Fifty percent of fibroids are asymptomatic and require no treatment, but the rest may cause menorrhagia, dysmenorrhoea, dyspareunia, abdominal disten...

OBJECTIVES Magnetic resonance imaging (MRI)-guided high intensity focused ultrasound surgery (MRgFUS) is a newly emerging non-invasive technique for the treatment of uterine fibroids. The purpose of this study is to review the clinical impact of MRgFUS. METHODS This study examined 157 patients. The high intensity focused ultrasound (HIFU) utilized in this study was Philips Achieva 1.5 Tesla M...

INTRODUCTION Uterine leiomyomas are the most common benign gynecologic tumors. To date laparoscopy myomectomy is the gold standard for treatment of symptomatic fibroids in reproductive-aged women. Detailed counseling about the effects of this procedure on postoperative sexuality and quality of life is important in these patients. However, available data on these subjects are limited and contrad...

Purpose: To compare costs and reimbursements for three different treatments for uterine fibroids. Methods: Costs and reimbursements were collected and analyzed from the Thomas Jefferson University Hospital decision support database from 540 women who underwent abdominal hysterectomy (n = 299), abdominal myomectomy (n = 105), or uterine fibroid embolization (UFE) (n = 136) for uterine fibroids d...

Background: Uterine leiomyoma is a very common benign smooth muscle tumor of the uterus. It isthe most frequent benign neoplasm in women of reproductive age and could have a harmful impact on the reproductive system. Insulin-like growth factor–I (IGF-I) plays a vital role in the pathogenesis of fibroids. Aim: To find out the relationship of uterine leiomyoma with insulin like growth factor -1. ...

OBJECTIVE To compare the cost and quality-adjusted life-years (QALYs) of hysterectomy, myomectomy, and uterine artery embolization (UAE) for symptomatic control of uterine fibroids. DESIGN A cost-utility analysis conducted by using Markov modeling. SETTING The analysis was conducted from the perspective of Hong Kong society. PATIENT(S) A hypothetical cohort of patients presenting with sym...

Background: Gynecologic conditions including uterine fibroids, adenomyosis and endometriosis lead to significant impairment in women’s’ lives and significant expen- Abstracts of the 12th Royan International Congress on Reproductive Biomedicine International Journal of Fertility & Sterility (IJFS), Vol 5, Suppl 1, Summer 2011 24 ditures of health care dollars. However, many women have symptoms l...

fibroids are the most common benign tumors of the uterus during female reproductive age. uterine artery embolization (uae) using embolic particles (pva, gelfoam) to occlude the uterine arteries, have been reported as a relatively safe, effective, and durable nonsurgical alternative to hysterectomy in diminishing fibroid-related symptoms. to block the arterial blood supply to the fibroid complet...

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