GADD153 is a CCAAT/enhancer-binding-protein-related gene that may function to control cellular growth in response to stress signals. In this study, a variety of oxidant treatments were shown to stimulate endogenous GADD153 mRNA expression and to transcriptionally activate a GADD153 promoter-reporter gene construct in transfected HeLa cells. Both commonalities and distinctions in the induction o...

The use of solvent/detergent mixtures and various forms of heat treatment to inactivate viruses has become widespread in the preparation of blood derivatives. Because viruses that lack lipid envelopes and/or are heat resistant, eg, hepatitis A virus (HAV) or parvovirus B19 may be present, the use of two methods of virus elimination that operate by different mechanisms has been advocated. We now...

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a structurally endogenous peptide with many biological roles. Maxadilan, a 61-amino acid vasodilatory peptide, specifically activates the PACAP type I receptor (PAC1). Although PAC1 has been identified in embryonic stem cells, little is known about its presence or effects in human induced pluripotent stem (iPS) cells. In the present ...

BACKGROUND: The control of coccidiosis in poultry industryis dominated by prophylactic chemotherapy; however,drug resistance is a serious problem. Alternative control methodssuch as vaccination have been accepted as a practical method forcontrolling coccidiosis in chickens. Considering the immunologicalvariation of Eimeria strains, the efficacy of live coccidiosisvaccines may be compromised. OB...

The current work aimed to evaluate the feasibility of including ozone (O3)-based advanced oxidation processes (AOPs), as an intermediate step, in a multistage treatment system for non-biodegradable sulphur-rich leachate from hazardous industrial solid waste landfill (HISWL), combining chemical and biological technologies. O3-based AOPs covered perozonation (O3/H2O2), photo-assisted ozonation (O...

This study aims to examine the mechanical properties of acrylonitrile butadiene styrene specimens using ASTM 638, 695, and 790. UVC radiation was also used as a sterilizing method. The fused deposition modeling 3D-printed polymerize with 30% filling manufacture 30 for tensile, compression, bending. Half were treated UVC, whereas other half not. chosen dosage 13.5 J/cm2 an exposure time 48 min c...

background: the control of coccidiosis in poultry industryis dominated by prophylactic chemotherapy; however,drug resistance is a serious problem. alternative control methodssuch as vaccination have been accepted as a practical method forcontrolling coccidiosis in chickens. considering the immunologicalvariation of eimeria strains, the efficacy of live coccidiosisvaccines may be compromised. ob...

The tumor suppressor p16, a phosphoprotein that exists in human cells under both phosphorylated and nonphosphorylated forms, plays crucial roles during the cellular response to UV light. However, it is still unclear how this protein is activated in response to this carcinogenic agent. We have shown here that UVC upregulates p16 and the phosphorylated form of the protein at the 4 serine sites; S...