H2O2-producing lactobacilli in the vaginal fluid have been suggested to play a potential tumor-preventive role in addition to the control of undesirable microorganisms. As the vaginal fluid also contains a significant concentration of peroxidase that might utilize lactobacilli-derived H2O2 as substrate for HOCl synthesis, a dominant biological role of HOCl in both natural defence systems has be...

The aim of our study was to develop a liposomal carrier system for the local treatment of bacterial vaginosis, capable to efficiently deliver entrapped drug during an extended period of time. Chloramphenicol was entrapped in liposomes composed of egg phosphatidylcholine/egg phosphatidylgycerol-sodium (9:1, molar ratio) and prepared by two different methods, the proliposome method and the polyol...

1. Human placenta microsomes active in blood coagulation have been prepared by a combination of differential centrifugation, density gradient centrifugation, and extraction with butanol-benzene mixtures. Human brain particles have been prepared from acetone-dried brain by extraction with sodium chloride solutions, differential centrifugation, and extraction with butanol-benzene mixtures. 2. Pla...

background: the incidence of ectopic pregnancy varies between 1.5-2% of all pregnancies. bilateral tubal ectopic pregnancy is rare. it may occur in 1 per 200 000 pregnancies. case: this is a case report of 25 year-old woman who underwent intra uterine insemination (iui), because of tubal factor infertility (unilateral). on the 30pthp day after the iui she complained from pelvic pain and vaginal...

The retention of the antibiotic chloramphenicol on, and penetration into, the rabbit eye has been compared following administration in two vehicles. Samples were taken of both aqueous humor and a washing fluid applied to the conjunctival surface and the concentration of 14C-chloramphenicol determined. Greater tear film and aqueous humor drug concentrations, which are effective against many orga...

was fluctuating, so evidently contained fluid, and as it had recently become painful, presumably pus. A long incision was made through the tumour, and a large quantity of pus was evacuated, mixed with which was a lot of short hair, like a handful of cropped hair on washing out the cavity, it was found to contain three or four long hairs, whose roots wore firmly fixed to the base of the tumour. ...

Idoxifene, a tissue-specific selective estrogen receptor modulator, was evaluated in male and female rats and female rabbits after oral administration for effects on fertility and/or embryo-fetal development. In all studies, adult toxicity was evident at doses >/=0.03 mg/kg/day in rats and >/=0.1 mg/kg/day in rabbits as evidenced by decreased body weight and/or food consumption. In the male fer...

Humoral (antibody [Ab]) and cellular Candida-specific immune responses in the vaginas of pseudoestrus rats were investigated during three successive infections by Candida albicans. After the first, protective infection, Abs against mannan and aspartyl proteinase antigens were present in the vaginal fluid, and their titers clearly increased during the two subsequent, rapidly healing infections. ...

PURPOSE To describe the maternal and fetal outcomes with the use of the Foley catheter for induction of labor in high-risk pregnant women with previous caesarean section. METHODS An interventive and descriptive study was conducted from November 2013 to June 2014. A total of 39 pregnant women at term, with a live fetus, cephalic presentation, estimated fetal weight <4,000 g, with previous cesa...