See page 2131 for definitions of strength-ofrecommendation labels. V aginitis is among the most common conditions for which women seek medical care, with vaginal discharge accounting for approximately 10 million office visits each year.1 Although vaginitis can have a variety of causes (Table 1), it most often is associated with infection or atrophic changes. Common infectious forms of vaginitis...

In healthy humans, many microbial consortia constitute rich ecosystems with dozens to hundreds of species, finely tuned to functions relevant to human health. Medical interventions, lifestyle changes, and the normal rhythms of life sometimes upset the balance in microbial ecosystems, facilitating pathogen invasions or causing other clinically relevant problems. Some diseases, such as bacterial ...

BACKGROUND Fastidious bacteria have been associated with bacterial vaginosis (BV) using PCR methods. We assessed the prevalence of these bacteria in HIV-1 infected women and their relationship with vaginal pH and shedding of HIV-1 RNA. METHODS 64 cervicovaginal lavage (CVL) samples were collected from 51 women. Vaginal microbiota were characterized using 8 bacterium-specific quantitative PCR ...

Metronidazole is used to treat trichomoniasis, bacterial vaginosis, and other diseases. As is the case with many drugs, physicians often hesitate to use it during pregnancy, particularly in the first trimester. A review of the nearly four decades' worth of published literature on metronidazole use in pregnant women indicates that it is not teratogenic, regardless of the trimester in which it is...

OBJECTIVES In this study, 210 women with vaginal discharge and other symptoms/signs of genital pathology suggestive of vulvovaginal candidiasis (VVC) were involved in order to distinguish true WC and cytolytic vaginosis (CV) cases. METHODS Fungal cultures, 10% potassium hydroxide (KOH) and Gram stained preparations and pH measurements were performed on the vaginal discharge material of each p...

Forty-two healthy women were randomized to receive one of three encapsulated Lactobacillus rhamnosus GR-1 plus Lactobacillus fermentum RC-14 probiotic dosage regimens or L. rhamnosus GG by mouth each day for 28 days. However, the vaginal flora, assessed by Nugent scoring, was only normal in 40% of the cases, and 14 patients had asymptomatic bacterial vaginosis. Treatment with L. rhamnosus GR-1/...

Introduction: Bacterial vaginosis is the most common cause of vaginal discharge and occurs when there an imbalance in microbiota, predominantly composed Lactobacillus spp. Human Papillomavirus sexually transmitted virus world. Persistent infection with high-risk genotypes main development cervical intraepithelial neoplasia cancer. Objective: To investigate association between bacterial cytologi...

Introduction: Bacterial vaginosis is characterized by the imbalance of vaginal flora, with decrease in Lactobacillus and increase other bacteria. Objective: To investigate prevalence factors associated bacterial vaginosis. Methods: Systematic review based on guidelines Preferred Reporting Items for Reviews Meta-Analyses, filed International Prospective Register Reviews. The research was conduct...