Background: Calcified aortic valve disease (CAVD) is the most prevalent valvular that can be treated only through replacement. We aimed to explore potential biomarkers and role of immune cell infiltration in CAVD progression bioinformatics analysis.

Cardiac involvement is common in acromegaly, but the prevalence of valvular abnormalities in patients with acromegaly has not been documented and is the topic of this study. In a prospective study design, 40 consecutive patients with acromegaly and 120 control subjects (matched for age, sex, hypertension, and left ventricular systolic function) were studied. All patients and controls were evalu...

Calcification complications are frequent among long-term dialysis patients. However, the prognostic implication of cardiac valve calcification in this population is not known. This study aimed to determine if cardiac valve calcification predicts mortality in long-term dialysis patients. Baseline echocardiography was performed in 192 patients (mean +/- SD age, 55 +/- 12 yr) on continuous ambulat...

Valvular heart disease is a subject of growing interest due to its prevalence and difficult issues in decision-making in the rapidly moving field of percutaneous interventions. During this year, a number of interesting articles addressed the topic of valvular heart disease with a special emphasis on imaging, interventions, and the publication of the new European Society of Cardiology (ESC) guid...

Six cases of classical dissecting aneurysm of the aorta complicating aortic valvular disease in which aortic stenosis was dominant are described. In three of the cases the aortic complication occurred after the natural aortic valve had been replaced by a prosthetic valve. The longest postoperative period was four months. The factor common to all reported cases in our series was cystic medial ne...

AIM The aim of this study was to evaluate the diagnostic utility of natriuretic peptides of type A and B as noninvasive markers in the diagnosis and treatment of congenital and valvular heart disease. METHODS Blood samples from 82 patients with various congenital and valvular heart diseases were measured for A and B natriuretic peptide levels and levels compared with those in a reference grou...

lthough widely used for a multitude of indications, cardiovascular imaging plays a critical and irreplaceable role in the assessment of valvular heart disease. In many previous editorials, we have commented about the value of using multiple imaging modalities to gather critically important information for decisionmaking, but at the same time maintaining an awareness of the risk of duplication a...

The valvular disease usually involves two conditions: valvular stenosis and valvular insufficiency. Valvular stenosis occurs when a valve opening is smaller than normal due to stiff or fused leaflets. The narrowed opening may make the heart work very hard to pump blood through it. This can lead to heart failure. All four valves can be stenotic (hardened, restricting blood flow); the conditions ...