Acetylcholine esterase, al-antichymotrypsin, homovanillic acid (HVA), 3-methoxy-4-hydroxy-phenylenglycol (MHPG), norepinephrine, dopa­ mine, 5-hydroxy-indolacetic acid (5-HIAA), and 7-aminobutyric acid (GABA) in the serum and cerebrospinal fluid (CSF) were quantified. Posi­ tive wave with the latency about 300 msec (P300) and electroencephalog­ raphy (EEG) were examined in 10 patients with Alzh...

BACKGROUND/AIMS The goal of this study was to examine the reliability and validity of the Changsha version of the Montreal Cognitive Assessment (MoCA-CS) in ischemic cerebrovascular disease patients of Hunan Province, China, and to explore the optimal cutoff score for detecting vascular cognitive impairment-no dementia (VCI-ND) and vascular dementia (VD). METHODS Three hundred and thirty-eigh...

This prospective study aimed to investigate metamorphopsia in eyes with central retinal vein occlusion (CRVO) and included 28 eyes (28 patients) with unilateral CRVO that had macular edema (ME) in the acute phase. The ME was treated with anti-vascular endothelial growth factor agents. At baseline and at 1 and 6 months after initiation of treatment, quantitative measurements of metamorphopsia we...

BACKGROUND AND AIM The aim of this study is to highlight the presence of co-morbidities and their role in caring for chronicly ill patients with and without dementia. PATIENTS AND METHODS The study was performed on a group of 213 chronic patients. We used CIRS-G (Cumulative Illness Rating Scale in Geriatric Population) and IADL (Instrumental Activity Daily Living) scales. We compared the scor...

BACKGROUND Cardiovascular disease and vascular risk factors increase rates of cognitive impairment, but very little is known regarding prevention in this high-risk group. The heart-healthy Mediterranean-type dietary pattern may beneficially influence both vascular and cognitive outcomes. OBJECTIVES We examined the association between Mediterranean-style diet and cognitive decline in women wit...

We conducted a randomized, double-blind, parallel-group study to assess the effect of 6 weeks treatment with low-dose (100 microg twice a day) or high-dose (500 microg twice a day) inhaled fluticasone propionate (FP) on the vascular component of airway remodeling in 30 patients with mild to moderate asthma. We also studied the effect on the inflammatory cells and the basement membrane thickness...

BACKGROUND Peripheral vascular interventions are increasingly preferred for the treatment of patients with symptomatic peripheral arterial disease because they are associated with similar clinical outcomes and lower morbidity than open surgical procedures. The objective of this study was to assess the comparative effectiveness of procedural anticoagulation with bivalirudin compared with unfract...

The aim of this study was to analyse breast carcinomas with discordant receptor status, probably hormonal dependent (estrogen receptor (ER) positive, progesterone receptor (PR) negative or ER-PR + subgroup profile) infiltrating ductal breast carcinomas not otherwise specified (IDC NOS). Specimens from 90 IDC NOS were grouped into three categories according to hormonal status: dependent (D) (ER ...

Pneumococcal meningitis is associated with substantial mortality and morbidity. We systematically assessed brain histopathology of 31 patients who died of pneumococcal meningitis from a nationwide study (median age 67 years; 21 (67 %) were male) using a pathology score including inflammation and vascular damage. Of the 27 patients with known time from the admission to death, 14 patients died wi...

background: intrapulmonary vascular abnormalities associated with liver cirrhosis may result in intrapulmonary right-to-left shunt and hypoxemia. the aim of this study was to use contrast enhanced echocardiography to detect intrapulmonary vascular abnormalities in patients with liver cirrhosis candidates for liver transplantation.   methods: one hundred and two adult patients underwent contrast...