rhabditidae is a family of free-living nematodes. free living nematodes due to their active movement and resistance to chlorination, do not remove in conventional water treatment processes thus can be entered to distribution systems and cause adverse health effects. ultraviolet radiation (uv) can be used as a method of inactivating for these organisms. this cross sectional study was done to inv...

We have recently treated with N2 gas plasma and achieved inactivation of bacteria. However, the effect of N2 gas plasma on viruses remains unclear. With the aim of developing this technique, we analyzed the virucidal effect of N2 gas plasma on influenza virus and its influence on the viral components. We treated influenza virus particles with inert N2 gas plasma (1.5 kpps; kilo pulses per secon...

Viral safety is an important prerequisite for clinical preparations of all biopharmaceuticals derived from plasma, cell lines, or tissues of human or animal origin. To ensure the safety, implementation of multiple viral clearance (inactivation and/or removal) steps has been highly recommended for manufacturing of biopharmaceuticals. Of the possible viral clearance strategies, Ultraviolet-C (UVC...

background and objectives: pathogen reduction technologies are among methods to eliminate transfusion transmitted infections. mirasol method using riboflavin in combination with ultraviolet rays is one of them. the aims of this study were to investigate the effectiveness of mirasol method to inactivate some model pathogens as well as examination of the sensitivity of plasma proteins after treat...

introduction: the purpose of this study was to compare the inhibitory effect of bovine serum albumin (bsa) and hydroxyapatite (ha) on the antibacterial activity of white-colored mta (wmta) against staphylococcus (s.) aureus and streptococcus (s.) mutans after 24 and 72 hours . materials & methods: all materials were prepared according to the manufacturer’s directions immediately before testing....

During purification of monoclonal antibodies, viral inactivation/removal step is a mandatory to comply with the regulatory guidelines which commonly performs at low pH about 3.5 and further neutralizes it 7.0. Neutralization antibodies results formation high turbidity troublesome for processing such as filtration other chromatography processes eventually leads filter clogging increases column b...

Background & Aims of the Study: The heterotrophic bacteria are widely used as a water microbial pollution index for drinking water. The aim of this study was to investigate the effect of metallic nanoparticles such as Zero Valent Iron (ZVI), Titanium dioxide (TiO2) and Zinc oxide (ZnO) on Heterotrophic Bacter...

DESCRIPTION Carimune® NF, Nanofiltered, Immune Globulin Intravenous (Human), is a sterile, highly purified polyvalent antibody product containing in concentrated form all the IgG antibodies which regularly occur in the donor population.1 This immunoglobulin preparation is produced by cold alcohol fractionation from the plasma of US donors. Part of the fractionation may be performed by another U...

the goal of this study was to determine the effects of the l-type calcium channel blockers verapamil and diltiazem on the currents of voltage-gated potassium channel (fkv1.4δn), an n-terminal-deleted mutant of the ferret kv1.4 potassium channel. measurements were made using a two electrode voltage clamp technique with channels expressed stably in xenopus oocytes. the fkv1.4δn currents displayed...

During the last decade an increased incidence of infections and outbreaks attributed to foodborne viruses, in particular noroviruses (NoV), was observed world wide. The awareness of the presence of viruses on food emphasized the need to acquire knowledge regarding the effect of preservation methods upon viruses. Most foodborne viruses cannot be cultured in the laboratory, which hinders studies ...