BACKGROUND Norovirus, formerly known as Norwalk virus, is an important cause of gastroenteritis outbreaks in hospitals, food services, schools, and cruise ships. Infection control practices by using disinfectants to eliminate noroviruses from surfaces and environmental samples reduce the morbidity and spread of virus outbreaks. There are not many commercial disinfectants effective against norov...

In article number 2100044, Lopes and co-workers discuss the progress in materials designed against viruses. Antiviral mechanisms, such as virucidal, virus binding, drug delivery, are reviewed. The study evaluates several antiviral materials, from bulk to nanoparticles, their applications targeting different

Background Viral infections often pose tremendous public health concerns as well as economic burdens. Despite the availability of vaccines or antiviral drugs, personal hygiene is considered as effective means as the first-hand measure against viral infections. The green tea catechins, in particular, epigallocatechin-3-gallate (EGCG), are known to exert potent antiviral activity. In this study, ...

Photochemical damage either to retinoids by near-ultraviolet radiation or to unsaturated fatty acids by near-ultraviolet radiation in the presence of a hydrophobic photosensitizer destroys the virucidal activities of the compounds, as determined by studies on the enveloped bacteriophage ø6.

Although vaccines have been developed for rotavirus infections, there is currently no effective therapeutic treatment. Therefore, this study aimed to evaluate the efficacy of 18-hydroxyferruginol ( 1 ) and 18-oxoferruginol 2 isolated from Torreya nucifera (T. nucifera) against bovine G8P[7] porcine G5P[7] rotaviruses using two different assay strategies: 1) reduction viral infectivity by neutra...

Development of effective and environmentally friendly disinfectants, or virucidal agents, should help prevent the spread of infectious diseases through human contact with contaminated surfaces. These agents may also be used, if non-toxic to cells and tissues, as chemotherapeutic agents against infectious diseases. We have shown that arginine has a synergistic effect with a variety of virucidal ...