Subjective and autonomic responses to visual stimulation and facial pain were investigated in 10 migraine sufferers and 21 'non-headache' control subjects. Ratings of glare- and light-induced pain were greater in migraine sufferers than control subjects. In migraine sufferers, glare ratings increased during painful mechanical stimulation of the nasal ala, the side of the nose and the back of th...

The hemodynamic mechanism of increase in cerebral blood flow (CBF) during neural activation has not been elucidated in humans. In the current study, changes in both regional CBF and cerebral blood volume (CBV) during visual stimulation in humans were investigated. Cerebral blood flow and CBV were measured by positron emission tomography using H(2)(15)O and (11)CO, respectively, at rest and duri...

Multivariate analysis of functional magnetic resonance imaging (fMRI) data allows investigations into network behavior beyond simple activations of individual regions. We apply group independent component analysis to fMRI data collected in a previous study looking at the sustained neuromodulatory effects of electrical tongue stimulation in balance-impaired individuals. Twelve subjects with bala...

In 1930 Berger2 reported that visual stimulation by opening of the eyes in a lighted room blocked the occipital brain waves, while opening of the eyes in a dark room did not alter the occipital rhythm. The effect of visual stimulation on the so-called alpha rhythm was subsequently described by many authors, including Adrian and Matthews,' Fischer,4 Gibbs and Gibbs,5 Golla, Hutton, and Walter,7 ...

Background: An imbalance of the cerebrovascular response during functional activation of the brain has been postulated as a factor in the pathophysiology of migraine. The purpose of this study was to determine the transcranial doppler sonography (TDS) diagnostic value for the cerebral flow velocity changes in the interictal phase of classic migraine. Methods: This study was carried out on 46 pa...

We studied whether detectable percepts could be produced by electrical stimulation of intracranial electrodes placed over human visual areas identified with fMRI. Identification of areas was confirmed by recording local-field potentials from the electrode, such as face-selective electrical responses from electrodes over the fusiform face area (FFA). The probability of detecting electrical stimu...

BACKGROUND AND PURPOSE Severe atherosclerotic disease of the carotid arteries may affect perfusion in the posterior circulation according to the degree of collateral supply. The purpose of this study was to determine whether the responses of regional cerebral blood flow (rCBF) and regional cerebral metabolic rate of oxygen (rCMRO2) during neural stimulation are affected by the baseline perfusio...

In the present study, we introduce a new dual-frequency stimulation method that can produce more visual stimuli with limited number of stimulation frequencies for use in multiclass steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) systems. Methods for increasing the number of visual stimuli are necessary, particularly for the implementation of multi-class SSVEP-b...

Steady-state visual evoked potential (SSVEP) is one of the typical stimulation paradigms of brain-computer interface (BCI). It has become a research approach to improve the performance of human-computer interaction, because of its advantages including multiple objectives, less recording electrodes for electroencephalogram (EEG) signals, and strong anti-interference capacity. Traditional SSVEP u...

The central hub of the cortical vestibular network in humans is likely localized in the region of posterior lateral sulcus. An area characterized by responsiveness to visual motion has previously been described at a similar location and named posterior insular cortex (PIC). Currently it is not known whether PIC processes vestibular information as well. We localized PIC using visual motion stimu...