BACKGROUND The major cause of visual impairment in diabetic patients is macular edema. The failure of laser photocoagulation in a large subgroup of patients with clinically significant diabetic macular edema has prompted interest in other treatment methods. OBJECTIVES To evaluate the long-term efficacy and safety of an intravitreal injection of triamcinolone acetonide for clinically significa...

OBJECTIVES To compare methods to estimate the incidence of visual field progression used by 3 large randomized trials of glaucoma treatment by applying these methods to a common data set of annually obtained visual field measurements of patients with glaucoma followed up for an average of 6 years. METHODS The methods used by the Advanced Glaucoma Intervention Study (AGIS), the Collaborative I...

OBJECTIVES To report on the efficacy and safety of intravitreal aflibercept in patients with macular edema secondary to central retinal vein occlusion (CRVO) in an integrated analysis of COPERNICUS and GALILEO. PATIENTS AND METHODS Patients were randomized to receive intravitreal aflibercept 2 mg every 4 weeks or sham injections until week 24. From week 24 to week 52, all intravitreal afliber...

OBJECTIVES The aim of this study was to describe the management protocol for intermittent testicular torsion (ITT) in adults and report the outcome of this clinical condition, which is commonly overlooked in adults. SUBJECTS AND METHODS Sixty-three patients were included in the study. The inclusion criterion was the presence of sudden intermittent testicular pain over a duration of 3 months. ...

OBJECTIVES A sphenoid sinus fungal ball is a rare disease that can cause visual disturbances. Most afflicted patients remain in an indolent state. However, once the visual disturbance has occurred, the recovery rate is very low. The purpose of this study was to overview the clinical characteristics of patients with a sphenoid sinus fungal ball and ascertain factors possibly related to the occur...

OBJECTIVES Adverse drug reactions interfere with the standard treatment of pulmonary Mycobacterium avium complex (MAC) disease; however, few studies have investigated this issue. We studied adverse drug reactions in the treatment of pulmonary MAC disease. SUBJECTS We retrospectively examined 74 patients who underwent treatment for pulmonary MAC disease in our hospital between January 2001 and...

BACKGROUND Despite having the largest population in Africa, Nigeria has no accurate population based data to plan and evaluate eye care services. A national survey was undertaken to estimate the prevalence and determine the major causes of blindness and low vision. This paper presents the detailed methodology used during the survey. METHODS A nationally representative sample of persons aged 4...

ABSTRACT Objectives: Evaluate the treatment outcome and performance of uCentum spinal fixation system in treating traumatic, degenerative, tumoral diseases spine. Methods: This is a therapeutic study to investigate outcomes level evidence III, including twenty-three adult patients both sexes undergoing surgical degenerative (13 patients), traumatic (04 or tumor (06 patients). Patients were pros...

OBJECTIVES/HYPOTHESIS To examine the efficacy and tolerability of topical mupirocin for the management of surgically recalcitrant chronic rhinosinusitis (CRS) associated with Staphylococcus aureus infection. STUDY DESIGN Prospective open-label pilot study. METHODS Patients with surgically recalcitrant CRS who had positive nasendoscopically guided cultures for Staphylococcus aureus were trea...