This paper describes experiments conducted with membranous and soluble fractions obtained from Escherichia coli that had been grown on succinate, malate, or enriched glucose media. Oxidase and dehydrogenase activities were studied with the following substrates : nicotinamide adenine dinucleotide, reduced form (NADH), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH), succinate, ...

The purpose of the present study was to evaluate the impact of vitamin E and selenium (Se) supplementation on the performance, egg quality and hatchability of eggs from Japanese breeding quails. The experiment was conducted over a 60 day period using 135 quails in a completely randomized design (CRD) with two levels of vitamin E and two levels of selenium (80 mg/kg of vitamin E+0.2 mg/kg organi...

a total of 240, one-day-old quail chicks (coturnix coturnix japonica) were used to study the effects of artichoke leaf meal (alm) and vitamin e in diet on growth performance, ileal microbial populations and intestinal morphology in a 42-d trial. this experiment was performed as a completely randomized design with 4 replicates of 15 quails each, using a 4 × 2 factorial arrangement with diet and ...

the objective of this study was to evaluate quality of frozen-thawed bull semen processed with extenders containing vitamin c and e as antioxidants. pooled semen's were collected from 5 bulls and diluted to a concentration of 30 × 106 sperm/ml with citrate –egg yolk (cey) or tris – egg yolk (tey) extenders. the diluted semen was divided to 5 aliquots including control and 4 experimental groups....

Tenofovir disoproxil fumarate (TDF), the bisphosphonate ester prodrug of tenofovir (TFV), has poor bioavailability due to intestinal degradation and efflux transport. Reformulation using U.S. Food and Drug Administration-approved esterase and efflux inhibitors to increase oral bioavailability could provide lower dose alternatives and reduce costs for patients with HIV in resource-limited settin...

background: cyclosporine a (csa) is a nephrotoxic immunosuppressive drug. antioxidants might attenuate its toxicity. in the present study, the effects of vitamin e and quercetin on the morphology of kidney in csa-treated rats were investigated.   methods: six groups of rats were used in this gavage feeding study either for 4 or 8 weeks. groups 1 and 2 received either olive oil or 25% ethanol in...

Despite considerable effort focusing on designing and finding efficient anti-cancer drugs over the last decade, little progress has been achieved, in particular in case of highly recalcitrant malignancies. Also, since there is a trend suggesting that deaths from cancers may be more frequent than from cardiovascular diseases, it is important to look for novel efficient and selective therapeutic ...

The underlying mechanisms of alpha-tocopheryl succinate (alpha-TOS)-mediated apoptosis are not understood in detail, although the redox-silent vitamin E analog is a potent apoptogen and anti-cancer agent. Our previous studies showed the important role of Fas signaling in apoptosis induced by the mitocan. The objective of the present study was to investigate whether apoptosis triggered by alpha-...

In the aerobic tricarboxylate cycle succinate is formed via oxidation of a-ketoglutarate, but anaerobically various bacteria form it via reduction of fumarate. The latter pathway was initially inferred to account for the large amounts of succinate and its derivative, propionate, produced in the fermentation of glycerol by propionic bacteria (l-4). Furthermore, fumarate was later shown to serve ...