OBJECTIVES To evaluate in extremely low gestational age newborns, relationships between indicators of hypotension during the first 24 postnatal hours and developmental delay at 24 months of age. METHODS The 945 infants in this prospective study were born at <28 weeks, were assessed for three indicators of hypotension in the first 24 postnatal hours, and were evaluated with the Bayley Mental D...

BACKGROUND Intracranial arterial stenosis (ICAS) is the predominant cause of ischemic stroke and transient ischemic attack in Asia. Change of signal intensities (SI) across an ICAS on magnetic resonance angiography (MRA) may reflect its hemodynamic severity. METHODS In-patients with a symptomatic single ICAS detected on 3D time-of-flight MRA were recruited from 2 hospitals. Baseline and 1-yea...

Annual volume of pancreatic resections has been shown to affect mortality rates, prompting recommendations to regionalize these procedures to high-volume hospitals. Implementation has been difficult, given the paucity of high-volume centers and the logistical hardships facing patients. Some studies have shown that low-volume hospitals achieve good outcomes as well, suggesting that other factors...

Relationships between health care process performance measures (PPMs) and outcomes can differ in magnitude and even direction for patients versus higher level units (e.g., health care facilities). Such discrepancies can arise because facility-level relationships ignore PPM-outcome relationships for patients within facilities, may have different confounders than patient-level PPM-outcome relatio...

BACKGROUND Although teacher-student relationships lie at the heart of students' schooling experience, fundamental questions regarding these relationships remain unanswered. AIMS This study investigates three related questions about these relationships: To what extent do they change from the beginning to the end of a school year? Are any emergent changes associated with shifts in students' aca...

BACKGROUND Data suggest that the amygdala and hippocampus contribute to cocaine seeking and use, particularly following exposure to cocaine-related cues and contexts. Furthermore, indices of pre-treatment cocaine-use severity have been shown to correlate with treatment outcome in cocaine-dependent patients. METHODS The aim of this study was to assess the relationships between amygdalar and hi...

INTRODUCTION: There is a growing interest in identifying provider and hospital characteristics associated with improved patient outcomes for surgical procedures. Increased operative volume has been associated with benefits in patient centric and economic outcomes for a variety of surgical procedures. In ventral hernia repair, however, there has been a paucity of studies assessing the associatio...

INTRODUCTION: There is a growing interest in identifying provider and hospital characteristics associated with improved patient outcomes for surgical procedures. Increased operative volume has been associated with benefits in patient centric and economic outcomes for a variety of surgical procedures. In ventral hernia repair, however, there has been a paucity of studies assessing the associatio...

An inverse relationship between the annual number of patients treated by a hospital or physician and rates of mortality and complications has been repeatedly documented. These volume-outcome relationships have been explored in particular detail in cardiovascular medicine, including for procedures such as coronary artery bypass graft surgery and coronary angioplasty and conditions such as acute ...