Personalized search engines must be able to cope with various user preferences, retrieving the best matches to a query. For SQL and XML applications new methods for such preference-based searches have been implemented recently. Here we adopt this approach to keyword search in full-text search engines. We propose to augment the vector space model (VSM) by preference constructors having an intuit...

We make the case for virtual shared memory (VSM) for supporting future many-core chips. VSM is a shared memory abstraction implemented over distributed memory by a hypervisor, providing the operating system direct access to all memory in the system. VSM on a distributed-memory system, such as a many-core chip with local memory associated with each core or small group of cores, provides a non-un...

This study determined the effects of hypoxia on diameter, vascular smooth muscle (VSM) transmembrane potential (E(m)), and vascular cAMP levels for in vitro cannulated skeletal muscle resistance arteries (gracilis arteries) from Sprague-Dawley rats fed a low-salt (LS) or a high-salt (HS) diet. Arterial diameter and VSM E(m) were measured in response to hypoxia, iloprost, cholera toxin, forskoli...

The vector space model (VSM) emerged for almost three decades as one of the most effective approaches in the area of Information Retrieval (IR), thanks to its good compromise between expressivity, effectiveness and simplicity. Although Information Retrieval and Information Filtering (IF) undoubtedly represent two related research areas, the use of VSM in Information Filtering is much less analy...

Madagascine (3-isopentenyloxyemodin) can be chemically synthesized or purified from several Rhamnus species, and it is found to have more potent biological activities than the parent compound emodin. The aim of this study is to characterize the vasodilatory effect of madagascine on vasoconstriction and sphingosylphosphorylcholine induced vasospasm in ex vivo and reveal the potential mechanisms ...

In World Wide Web environments, recommender systems are useful to reduce information overloading. A content-based recommender system recommends items according to their features. Vector Space Model (VSM) is a popular way to recommend items that are similar to those the user liked in the past. The main disadvantages of this content-based method are overspecialization and new user problems that i...

We describe voltage-switching mode scanning electrochemical microscopy (VSM-SECM), in which a single SECM tip electrode was used to acquire high-quality topographical and electrochemical images of living cells simultaneously. This was achieved by switching the applied voltage so as to change the faradaic current from a hindered diffusion feedback signal (for distance control and topographical i...

Rho kinase (ROCK)-dependent vasoconstriction has been implicated as a major factor in chronic hypoxia (CH)-induced pulmonary hypertension. This component of pulmonary hypertension is associated with arterial myogenicity and increased vasoreactivity to receptor-mediated agonists and depolarizing stimuli resulting from ROCK-dependent myofilament Ca(2+) sensitization. On the basis of separate line...

In vivo, vascular smooth muscle (VSM) cells change their contractile phenotype toward a more proliferative phenotype during the pathogenesis of vascular diseases. Because these dedifferentiated VSM cells may gradually regain contractile functions, we aimed to identify signaling pathways that result in an increased expression of contractile proteins in VSM cells. In vitro, serum and thrombin ind...

To investigate the contribution of the vestibular velocity-storage mechanism (VSM) to the vertical rotational vestibulo-ocular reflex (rVOR) we recorded eye movements evoked by off-vertical axis rotation (OVAR) using whole-body constant-velocity pitch rotations about an earth-horizontal, interaural axis in four healthy human subjects. Subjects were tumbled forward, and backward, at 60 deg/s for...