Removal of genital warts by thermocautery was performed in 108 patients (57 men and 51 women) under topical anaesthesia with a local anaesthetic cream, lidocaine and prilocaine (EMLA). Most men had warts in the preputial cavity, most women had warts situated on the mucous membranes of the vulva, and warts at multiple sites were common. About 1 ml of cream per lesion was applied to the warts for...

Background Oral manifestations (such as warts) of HIV infection are evident of disease progression, occurring in 30–80% of affected population. Recent evidence indicates that Human Papillomavirus (HPV) related diseases are increased in the oral cavity of HIV seropositive individuals irrespective of HAART. This study was undertaken to evaluate prevalence of oral HPV infection in Indian HIV serop...

BACKGROUND Condyloma acuminata are soft, skin colored, fleshy warts that are caused by the Human Papilloma Virus (HPV). The disease is highly contagious, can appear singly or in groups, small or large. The incubation period may be from 1-6 months. Although anogenital warts are considered to be sexually transmitted in adults, this may not be the case for children. Genital warts in children may r...

Cell competition is a homeostatic mechanism that regulates the size attained by growing tissues. We performed an unbiased genetic screen for mutations that permit the survival of cells being competed due to haplo-insufficiency for RpL36. Mutations that protect RpL36 heterozygous clones include the tumor suppressors expanded, hippo, salvador, mats, and warts, which are members of the Warts pathw...

BACKGROUND The atypical Fat cadherin has long been known to control cell proliferation and organ size in Drosophila, but the mechanism by which Fat controls these processes has remained elusive. A newly emerging signaling pathway that controls organ size during development is the Salvador/Warts/Hippo pathway. RESULTS Here we demonstrate that Fat limits organ size by modulating activity of the...

BACKGROUND Viral warts are a common infectious disease and liquid nitrogen cryotherapy is one of the most common methods for treatment of these warts. Hand-foot viral warts frequently recur and reduce quality of life as well. OBJECTIVE To find the ideal treatment interval between cryotherapy sessions that can influence not only the cure rate but also the recurrence rate for hand-foot viral wa...

BACKGROUND There exists a treatment challenge with periungual warts. Topical immunotherapy with diphenylcyclopropenone (DPCP) has recently been reported to be an effective treatment for recalcitrant warts, including periungual types. OBJECTIVE We aimed to evaluate the effectiveness and preference of topical immunotherapy with DPCP in treating periungual warts. METHODS Twenty-seven patients ...

Background: Common resistant-to-therapy warts pose a challenge to both clinicians and patients. Among many destructive and immunotherapeutic options, no single, fully effective treatment has been suggested yet. Many investigations, including those using intralesional antigen administrations, have demonstrated that cellular immunity plays a major role in the clearance of human papilloma virus (H...

caused by human papilloma virus(HPV) coming from the papova family. They are a common dermatologic complaint, with an estimated incidence of 10% in children and young adults1. Commonly warts occur at the periungual areas and pose a problem in the management2 . Interferons have been used for the treatment of viral disease, cutaneous tumors, HIV-associated Kaposi’s sarcoma and other inflammatory ...

Anogenital warts represent a major therapeutic problem in genitourinary medicine. A wide range of treatment modalities is available (the usual indication that none is ideal). This therapeutic problem is not new; in the sixth century, Dionysius graphically described treatment of genital warts: "The surgeons spared neither iron nor fire, and were not moved to pity by the cries of the patients". B...