This study was intendent to examine if N-acetylcysteine (NAC) changes liver GSH levels and influences ChE serum activity in rats intoxicated with chlorfenvinphos. The studies were conducted on male Wistar rats of 200±20 g body weight. One group of rats was pretreated with 0.1% water solution of NAC. NAC was administered in drinking water 24h before intoxication. The control groups received oil ...

Alcohol addiction and intoxication are major health problems worldwide. Acute alcohol intoxication is well reported in adults and adolescents but less frequently reported in children of younger ages. We report three anonymized cases of pediatric ethanol exposure and illustrate the different mechanisms of intoxication. In all cases, a focused history is the key to prompt diagnosis and timely man...

Background: Unintentional drug intoxication is still a major cause of mortality and morbidity in young children. Method & Materials: In order to study changes of epidemiological indices of children intoxication during a 10-year period in Hamadan Province, all cases admitted to Ghaem Hospital from 1995-1999 were recruited, and compared with all cases admitted to the same hospital from 1990-1...

Abstract Background The urine immunochromatographic assay is a useful screening tool for patients suspected of acute drug intoxication in emergency conditions. Diphenhydramine shows symptoms similar to those tricyclic antidepressant (TCA) intoxication. Case presentation We examined case diphenhydramine showing cerebellar ataxia and prolonged false positive results TCA the urine. test showed per...

BACKGROUND Organophosphates are frequently used as insecticides in the household and in agricultural areas, thus posing a risk for accidental exposure. OBJECTIVES To describe the characteristics, clinical course and outcome of 97 patients admitted to emergency rooms with a diagnosis of acute OP poisoning. METHODS The clinical details of 97 patients were collected from 6 different hospitals ...

Tamoxifen citrate (TAM), is widely used for treatment of breast cancer. It showed a degree of hepatic carcinogenesis. The purpose of this study was to elucidate the antioxidant capacity of green tea (Camellia sinensis) extract (GTE) against TAM-induced liver injury. A model of liver injury in female rats was done by intraperitoneal injection of TAM in a dose of 45mg Kg(-1) day(-1), i.p. for 7 s...