HYPOTHESIS Although elevations in white blood cell count (WBC) and platelet count (PC) after splenectomy for trauma constitute a physiologic event, certain WBC and PC patterns help differentiate patients with from those without sepsis. DESIGN Medical record and trauma registry record retrospective review. SETTING Academic level I trauma center. PATIENTS From February 1997 through May 2001...

AlphaIFN has recently been recognized as an adjuvant therapy to surgery in melanoma patients. A major issue is to select patients who will benefit from this therapy and to avoid toxicity in those who will not respond. The aim of this exploratory analysis was to identify the predictive factors of response to alphaIFN. The French cooperative group has recently shown that adjuvant therapy of melan...

OBJECTIVES This study was designed to determine the relationship between baseline white blood cell (WBC) count and angiographic and clinical outcomes in patients with unstable angina (UA)/non–ST-segment elevation myocardial infarction (NSTEMI) and to see if WBC count was a significant predictor of outcomes independent of other biomarkers. BACKGROUND Inflammation has been shown to play a role in...

To examine age-related change in the strength of the association of white blood cell count (WBC) with features of the metabolic syndrome (MS), body mass index, blood pressure, total cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, fasting plasma glucose, and uric acid were assessed as the components of the MS in 5,218 Japanese male office workers aged 23-59 yr. The subjec...