historically, central asia and the caucasus has been the source of important developments in the regional and global level. the whole geopolitical theories in the 20th and 21st century paid special attention to this area. geopolitical status of the region has posed challenges for residents and even neighbors of the region. these challenges can be described as the divergence factors. therefore, ...

Chromosomal common fragile sites (CFSs) are specific mammalian genomic regions that show an increased frequency of gaps and breaks when cells are exposed to replication stress in vitro. CFSs are also consistently involved in chromosomal abnormalities in vivo related to cancer. Interestingly, several CFSs contain one or more tumor suppressor genes whose structure and function are often affected ...

Electron beam (e-beam) lithography using polymer resists is an important technology that provides the spatial resolution needed for nanodevice fabrication. But it is often desirable to pattern nonplanar structures on which polymeric resists cannot be reliably applied. Furthermore, fragile substrates, such as free-standing nanotubes or thin films, cannot tolerate the vigorous mechanical scrubbin...

We investigate jammed granular matter in a slowly rotating drum partially filled with granular material and find a state of polydirectional stability. In this state, the material responds elastically to small stresses in a wide angular interval while it responds by plastic deformation when subjected to small stresses outside this interval of directions. We describe the evolution of the granulat...

The fragile X mental retardation protein (FMRP) is an RNA-binding protein that regulates mRNA metabolism. FMRP has been largely studied in the brain, where the absence of this protein leads to fragile X syndrome, the most frequent form of inherited intellectual disability. Since the identification of the FMRP gene in 1991, many studies have primarily focused on understanding the function/s of t...

It happens increasingly often that experts need to collaborate in order to exchange ideas, views and opinions on their path towards understanding. However, every collaboration process is inherently fragile and involves a large set of human subjective aspects, including social interaction, personality, and emotions. In this paper we present Pogat, an a↵ective virtual agent designed to support th...