نتایج جستجو برای: white matter lesions
تعداد نتایج: 526058 فیلتر نتایج به سال:
Myelin loss is a severe pathological hallmark common to a number of neurodegenerative diseases, including multiple sclerosis (MS). Demyelination in the central nervous system appears in the form of lesions affecting both white and gray matter structures. The functional consequences of demyelination on neuronal network and brain function are not well understood. Current therapeutic strategies fo...
In a patient with features indicating the presence of pseudotumor cerebri, a negative cranial CT-scan is not adequate to rule out less benign pathology and an MRI of brain should be performed. In this study, a 10-year old boy with daily headaches for one month and diplopia for one week was found to have a partial abducens palsy and bilateral papilledema; otherwise, his examination was normal. A...
White matter lesions are defining characteristics of multiple sclerosis (MS), whereas grey matter involvement is a less recognised attribute. Recent investigations using dedicated imaging approaches have made it possible to depict cortical lesions. Additionally, grey matter atrophy may be estimated using various methods. Several studies have suggested that grey matter atrophy closely correlates...
INTRODUCTION Unilateral spastic cerebral palsy (US CP) is the second most common subtype of cerebral palsy. AIM The aim of the study was to analyze neuroimaging findings in children with unilateral spastic cerebral palsy. MATERIAL AND METHODS The study was hospital based, which has included 106 patients with US CP (boys 72/girls 34, term 82/preterm 24). Neuroimaging findings were classified...
Brain lesions induced in newborn mice or rats by the glutamatergic agonists ibotenate (acting on NMDA and metabotropic receptors) or S-bromowillardiine (acting on AMPA-kainate receptors) mimic some aspects of white matter cysts and transcortical necrosis observed in human perinatal brain damage associated with cerebral palsy. Exogenous and endogenous cannabinoids have received increasing attent...
Introduction: Methanol is a toxic material and is found as an ingredient of many products, such as anti freezes and washer fluid. Acute poisoning is a rare accidental or suicidal intoxication or occurs after ingestion of alcohol .Methanol poisoning can cause severe metabolic acidosis , neurologic dysfunction, visual loss, parkinsonism, and death. Basal ganglia necrosis, and subcortical white ...
OBJECTIVE CADASIL is a genetic paradigm of cerebral small vessel disease caused by NOTCH3 mutations that stereotypically lead to the extracellular deposition of NOTCH3 ectodomain (Notch3(ECD) ) on the vessels. TIMP3 and vitronectin are 2 extracellular matrix proteins that abnormally accumulate in Notch3(ECD) -containing deposits on brain vessels of mice and patients with CADASIL. Herein, we inv...
The segmentation of MRI scans of patients with white matter lesions (WML) is difficult because the MRI characteristics of WML are similar to those of gray matter. Intensity-based statistical classification techniques misclassify some WML as gray matter and some gray matter as WML. We developed a fast elastic matching algorithm that warps a reference data set containing information about the loc...
in this study, the vertical, transverse and oblique diameters of the spinal cord segments (c1, c6, c12, c18, t1, t4, l1, l4, l6 and l8) and the ratio of gray matter to white matter in chick (l month) and adult (18 months) male ostriches, each group consisted of 3 animals, were measured with standard micrometric method using 6 μm thick sections by light microscope. with advancement of age, the r...
We report the features of neuroimaging within 24 hours after birth in 2 siblings with molybdenum cofactor deficiency. The first sibling was delivered by emergency cesarean section because of fetal distress and showed pedaling and crawling seizures soon after birth. Brain ultrasound revealed subcortical multicystic lesions in the frontal white matter, and brain MRI at 4 hours after birth showed ...
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