Hemozoin, the black– brown crystalline byproduct from a parasite’s digestion of hemoglobin, aided the detection of malaria over a century ago when Ronald Ross won a Nobel Prize for his discovery of the transmission of malaria. Hemozoin was useful back then because little was understood of the parasite and hemozoin could be seen without a stain. For years the gold standard for diagnosing malaria...

Background Fever of unknown origin (FUO) has many possible causes, so detailed history taking and physical examination are required. We identified key diagnostic features of medical history and physical findings for an efficient diagnosis of FUO. Methods A total of 42 consecutive patients (mean age: 50.6±20.3 years) with classic FUO were retrospectively recruited from January 2010 to March 20...

Antibiotic use is a modifiable driver of antibiotic resistance. In many circumstances, antibiotic use is overly broad or unnecessary. We systematically assessed factors associated with antibiotic prescribing for respiratory tract infections (RTI). Studies were included if they used actual (not self-reported or intended) prescribing data, assessed factors associated with antibiotic prescribing f...

Background: Annual patient effective dose equivalent can be considered as a quantitative physical parameter describing the activities performed in each nuclear medicine department. Annual staff dose equivalent could be also considered as a parameter describing the amount of radiation risk for performing the activities. We calculated the staff to patient dose equivalent ratio to be used as a phy...

INTRODUCTION AND OBJECTIVES Although congenital heart defects are the most common major congenital abnormalities, the associated mortality has been decreasing due to improvements in their diagnosis and treatment. We assessed the usefulness of 64-multidetector computed tomography in the diagnosis and management of these patients. METHODS This 5-year observational, analytical, retrospective, co...

an 18-year-old girl fulfilled the diagnostic criteria for the proteus syndrome (ps). here we report our findings in comprehensive general physical and ocular examination and review the literature focused on clinical manifestations and differential diagnoses. the patient had ‘mild’ involvement of the ophthalmic apparatus: absent foveal reflex, cataract, and abnormal retinal vessels, which in the...

Chronic interstitial lung disease (ILD) is a rare disorder in the paediatric age group, with a poor prognosis. The diagnostic approach to ILD is based on more or less invasive methods. This study was implemented to verify which methods are the most often used in children. Questionnaires (333) were sent to members of the European Respiratory Society Paediatric Assembly belonging to 187 European ...

interviewing, focused physical examination, and diagnostic assessment. At a weighty 640 pages, it is unlikely to find its way into many white coat pockets — an unfortunate fact given the clarity and utility of much of the information within. The first and largest section of the book comprises 17 chapters intended to direct history taking and physical examination across all organ systems, includ...